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Estudo retrospetivo e prospetivo de tumores mamários em gatas
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| 6.85 MB | Adobe PDF |
Advisor(s)
Abstract(s)
Ao longo dos anos tem havido um aumento da incidência de tumores mamários em felinos,
sobretudo em fêmeas. Os tumores mamários são o terceiro tumor mais comum em gatas (17%).
Para esta dissertação de mestrado foi realizado um estudo retrospetivo e prospetivo que teve
como objetivo analisar uma amostra de gatas com neoplasia mamária (n=40). A recolha dos dados,
através das fichas clínicas, relativamente a estas gatas decorreu durante o período de estágio, desde
9 de setembro de 2017 a 3 de março de 2018, no Hospital Veterinário do Porto, Clínica Veterinária dos
Gatos e Hospital Veterinário de Berna em Lisboa.
Realizou-se uma comparação entre o tempo livre de doença (TLD) e tempo de sobrevivência (TS)
com o estadio clínico, tamanho do tumor, invasão dos linfonodos, mestastização à distância, tipo de
tumor, grau histológico, tratamento com quimioterapia e/ou cirurgia.
A média das idades das gatas deste estudo foi de 10,95 anos, cerca de 57,5% das gatas não
lhes foi administrado contracetivos e 72,5% realizaram ovariohisterectomia. O carcinoma tubulopapilar
foi o mais observado (65%), e apenas 5% das gatas apresentaram tumor benigno. Relativamente a
recidivas, aconteceram em 37,5% das gatas e o local mais observado foram nas glândulas mamárias
adjacentes (20%). Em média o tempo livre de doença apresentou-se nos 586,3 dias e o tempo de
sobrevivência nos 511,8 dias.
Apenas se obteve uma associação estatisticamente significativa entre o tamanho tumoral e o
tempo de sobrevivência (p=0.03).
Over the years there has been an increase in the incidence of mammary tumors in felines, especially in female cats. Breast tumors are the third most common tumor in cats (17%). For this master’s thesis a retrospective and prospective study was carried out to analyze a sample of cats with breast neoplasia (n=40). The data collection, through the clinical records, for these cats took place during the training period, from September 9, 2017 to March 3, 2018, at the Veterinary Hospital do Porto, Clínica Veterinária dos Gatos and Hospital Veterinário de Berna. A comparison between disease-free time (TLD) and survival time (TS) was performed with clinical stage, tumor size, lymph node invasion, mestastization, tumor type, histological grade, treatment with chemotherapy and / or surgery. The average age of the cats in this study was 10.95 years, about 57.5% of the cats were not given contraceptives and 72.5% underwent ovariohysterectomy. Tubulo-papillary carcinoma was the most observed (65%), and only 5% of cats had a benign tumor. Regarding relapses, they occurred in 37.5% of the cats and the most observed site was in the adjacent mammary glands (20%). On average, the disease-free time was 586.3 days and the survival time was 511.8 days. Only a statistically significant relationship was obtained between tumor size and survival time (p=0.03).
Over the years there has been an increase in the incidence of mammary tumors in felines, especially in female cats. Breast tumors are the third most common tumor in cats (17%). For this master’s thesis a retrospective and prospective study was carried out to analyze a sample of cats with breast neoplasia (n=40). The data collection, through the clinical records, for these cats took place during the training period, from September 9, 2017 to March 3, 2018, at the Veterinary Hospital do Porto, Clínica Veterinária dos Gatos and Hospital Veterinário de Berna. A comparison between disease-free time (TLD) and survival time (TS) was performed with clinical stage, tumor size, lymph node invasion, mestastization, tumor type, histological grade, treatment with chemotherapy and / or surgery. The average age of the cats in this study was 10.95 years, about 57.5% of the cats were not given contraceptives and 72.5% underwent ovariohysterectomy. Tubulo-papillary carcinoma was the most observed (65%), and only 5% of cats had a benign tumor. Regarding relapses, they occurred in 37.5% of the cats and the most observed site was in the adjacent mammary glands (20%). On average, the disease-free time was 586.3 days and the survival time was 511.8 days. Only a statistically significant relationship was obtained between tumor size and survival time (p=0.03).
Description
Keywords
Gatas Tempo de sobrevivência Tempo livre de doença Tumores mamários Female Cats Survival time Disease-free time Mammary tumors