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Preparing and selecting actions with neural populations: toward cortical circuit mechanisms

dc.contributor.authorMurakami, Masayoshi
dc.contributor.authorMainen, Zachary F
dc.date.accessioned2018-06-29T15:25:42Z
dc.date.available2018-06-29T15:25:42Z
dc.date.issued2015-02-03
dc.description.abstractHow the brain selects one action among multiple alternatives is a central question of neuroscience. An influential model is that action preparation and selection arise from subthreshold activation of the very neurons encoding the action. Recent work, however, shows a much greater diversity of decision-related and action-related signals coexisting with other signals in populations of motor and parietal cortical neurons. We discuss how such distributed signals might be decoded by biologically plausible mechanisms. We also discuss how neurons within cortical circuits might interact with each other during action selection and preparation and how recurrent network models can help to reveal dynamical principles underlying cortical computation.pt_PT
dc.description.sponsorshipERC 250334, 5-HT Optogenetic
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1016/j.conb.2015.01.005pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/23194
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectCerebral Cortexpt_PT
dc.subjectDecision Makingpt_PT
dc.subjectModels, Neurologicalpt_PT
dc.titlePreparing and selecting actions with neural populations: toward cortical circuit mechanismspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage46pt_PT
oaire.citation.startPage40pt_PT
oaire.citation.titleCurrent Opinion in Neurobiologypt_PT
oaire.citation.volume33pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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