HPLC determination of theophylline and paracetamol in fresh and powdered milk

Fernandes, T.; Aguiar, J.; Pinto, J. F.; Fernandes, A. I.

Publication

HPLC determination of theophylline and paracetamol in fresh and powdered milk

2015-11-27Conference object

dc.contributor.author	Fernandes, T.
dc.contributor.author	Aguiar, J.
dc.contributor.author	Pinto, J. F.
dc.contributor.author	Fernandes, A. I.
dc.date.accessioned	2016-04-29T14:39:57Z
dc.date.available	2016-04-29T14:39:57Z
dc.date.issued	2015-11-27
dc.description	Poster presented at the 1st International Congress of CiiEM - From Basic Sciences to Clinical Research. 27-28 November 2015, Egas Moniz, Caparica, Portugal	pt_PT
dc.description.abstract	"Theophylline and paracetamol are drugs used worldwide both in human and veterinary medicine. Paracetamol (or acetaminophen) is employed as analgesic and antipyretic, and theophylline is a bronchodilator drug used in the treatment of asthma and chronic obstructive pulmonary disease. Both drugs are extensively used in pediatrics and their dosage is based on the child's body weight. Due to possible liver toxicity (paracetamol) and narrow therapeutic index (theophylline) it is imperative to carefully select and monitor the dose administered to children. Additionally, the recent proposal of milk as a platform to deliver drugs in pediatrics has prompted the development of a simple and sensitive high-performance liquid chromatography (HPLC) quantification method, of both theophylline and paracetamol, in the complex matrix that milk represents."	pt_PT
dc.description.sponsorship	Fundação para a Ciência e a Tecnologia (PTDC/DTP-FTO/1057/2012)	pt_PT
dc.identifier.uri	http://hdl.handle.net/10400.26/13405
dc.language.iso	eng	pt_PT
dc.relation	Powdered medicinal milks for oral delivery of drugs in paediatrics (MedMilk)
dc.subject	HPLC	pt_PT
dc.subject	Theophylline	pt_PT
dc.subject	Paracetamol	pt_PT
dc.subject	Milk	pt_PT
dc.subject	Fresh milk	pt_PT
dc.subject	Powdered milk	pt_PT
dc.title	HPLC determination of theophylline and paracetamol in fresh and powdered milk	pt_PT
dc.type	conference object
dspace.entity.type	Publication
oaire.awardTitle	Powdered medicinal milks for oral delivery of drugs in paediatrics (MedMilk)
oaire.awardURI	info:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FDTP-FTO%2F1057%2F2012/PT
oaire.citation.conferencePlace	Egas Moniz, Caparica, Portugal	pt_PT
oaire.citation.title	From Basic Sciences to Clinical Research - 1st International Congress of CiiEM	pt_PT
oaire.fundingStream	3599-PPCDT
project.funder.identifier	http://doi.org/10.13039/501100001871
project.funder.name	Fundação para a Ciência e a Tecnologia
rcaap.rights	openAccess	pt_PT
rcaap.type	conferenceObject	pt_PT
relation.isProjectOfPublication	a0df4380-9007-4eab-b38d-fd36fc6745f6
relation.isProjectOfPublication.latestForDiscovery	a0df4380-9007-4eab-b38d-fd36fc6745f6