HPLC determination of theophylline and paracetamol in fresh and powdered milk

Fernandes, T.; Aguiar, J.; Pinto, J. F.; Fernandes, A. I.

http://hdl.handle.net/10400.26/13405

Utilize este identificador para referenciar este registo.

Nome:	Descrição:	Tamanho:	Formato:
Poster 06_ProfAIFernandes.pdf		856.65 KB	Adobe PDF	Ver/Abrir
Poster 06_Abstract_ProfAIFernandes.pdf		66.71 KB	Adobe PDF	Ver/Abrir

Contacte-nos

Autores

Resumo(s)

"Theophylline and paracetamol are drugs used worldwide both in human and veterinary medicine. Paracetamol (or acetaminophen) is employed as analgesic and antipyretic, and theophylline is a bronchodilator drug used in the treatment of asthma and chronic obstructive pulmonary disease. Both drugs are extensively used in pediatrics and their dosage is based on the child's body weight. Due to possible liver toxicity (paracetamol) and narrow therapeutic index (theophylline) it is imperative to carefully select and monitor the dose administered to children. Additionally, the recent proposal of milk as a platform to deliver drugs in pediatrics has prompted the development of a simple and sensitive high-performance liquid chromatography (HPLC) quantification method, of both theophylline and paracetamol, in the complex matrix that milk represents."

Descrição

Poster presented at the 1st International Congress of CiiEM - From Basic Sciences to Clinical Research. 27-28 November 2015, Egas Moniz, Caparica, Portugal

Palavras-chave

HPLC Theophylline Paracetamol Milk Fresh milk Powdered milk

URI

http://hdl.handle.net/10400.26/13405

Projetos de investigação

Powdered medicinal milks for oral delivery of drugs in paediatrics (MedMilk)

Projeto de investigaçãoVer mais

Coleções

EM - Posters

Ver registo completo