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Effect of carrageenans on vegetable jelly in humans with hypercholesterolemia

2019-12-24Journal article Open access
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dc.contributor.authorValado, Ana
dc.contributor.authorPereira, Maria
dc.contributor.authorCaseiro, Armando
dc.contributor.authorFigueiredo, João
dc.contributor.authorLoureiro, Helena
dc.contributor.authorAlmeida, Carla
dc.contributor.authorCotas, João
dc.contributor.authorPereira, Leonel
dc.date.accessioned2021-03-05T19:24:34Z
dc.date.available2021-03-05T19:24:34Z
dc.date.issued2019-12-24
dc.description.abstractChanges in lipid profile constitute the main risk factor for cardiovascular diseases. Algae extracted carrageenans are long-chain polysaccharides and their ability to form gels provides for the formation of vegetable jelly. The objective was to evaluate the bioactive potential of carrageenan (E407) in the lipid profile, after ingestion of jelly. A total of 30 volunteers of both sexes, aged 20-64 years and with total cholesterol (TC) values ≥200 mg/dL, who ingested 100 mL/day of jelly for 60 days, were studied. All had two venous blood collections: before starting the jelly intake and after 60 days. At both times, TC, high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and triglycerides (TG), were evaluated using commercial kits and spectrophotometer. The statistics were performed using the SPSS 25.0 software and p < 0.05 were considered statistically significant. Serum values after 60 days of jelly intake revealed a statistically significant decrease in TC levels (5.3%; p = 0.001) and LDL-C concentration (5.4%; p = 0.048) in females. The daily intake of vegetable jelly for 60 days showed a reduction in serum TC and LDL-C levels in women, allowing us to conclude that carrageenan has bioactive potential in reducing TC concentration.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3390/md18010019pt_PT
dc.identifier.issn1660-3397
dc.identifier.urihttp://hdl.handle.net/10400.26/35834
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationMARE - Marine and Environmental Sciences Centre
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/pt_PT
dc.subjectCarrageenanpt_PT
dc.subjectTotal cholesterolpt_PT
dc.subjectCholesterol, HDLpt_PT
dc.subjectCholesterol, LDLpt_PT
dc.subjectTC reductionpt_PT
dc.subjectTriglyceridespt_PT
dc.subjectCarrageninapt_PT
dc.subjectColesterolpt_PT
dc.subjectHDL-Colesterolpt_PT
dc.subjectLDL-Colesterolpt_PT
dc.subjectTriglicerídeospt_PT
dc.titleEffect of carrageenans on vegetable jelly in humans with hypercholesterolemiapt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleMARE - Marine and Environmental Sciences Centre
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FMAR%2F04292%2F2019/PT
oaire.citation.endPage11pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleMarine Drugspt_PT
oaire.citation.volume18pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameValado
person.familyNameCaseiro
person.familyNameFigueiredo
person.familyNameCotas
person.familyNamePereira
person.givenNameAna Maria
person.givenNameArmando
person.givenNameJoão
person.givenNameJoão
person.givenNameLeonel
person.identifier758012
person.identifierM-3527-2013
person.identifier.ciencia-idF217-BA65-C0D2
person.identifier.ciencia-id4012-A0D8-66D6
person.identifier.ciencia-idF41B-EC2F-917F
person.identifier.ciencia-id0316-292F-A852
person.identifier.ciencia-id3714-5552-19FE
person.identifier.orcid0000-0002-0157-6648
person.identifier.orcid0000-0001-7844-0506
person.identifier.orcid0000-0002-9829-1592
person.identifier.orcid0000-0002-5244-221X
person.identifier.orcid0000-0002-6819-0619
person.identifier.ridL-8385-2013
person.identifier.ridJOZ-8716-2023
person.identifier.ridC-1487-2019
person.identifier.scopus-author-id35738464000
person.identifier.scopus-author-id56321727300
person.identifier.scopus-author-id57205649257
person.identifier.scopus-author-id7201962433
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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