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Opioid Monitoring in Clinical Settings: Strategies and Implications of Tailored Approaches for Therapy

2024Journal article Open access
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dc.contributor.authorRosendo, Luana M.
dc.contributor.authorRosado, Tiago
dc.contributor.authorZandonai, Thomas
dc.contributor.authorRincon, Karem
dc.contributor.authorPeiró, Ana M.
dc.contributor.authorBarroso, Mário
dc.contributor.authorGallardo, Eugenia
dc.date.accessioned2024-08-08T09:03:34Z
dc.date.available2024-08-08T09:03:34Z
dc.date.issued2024
dc.description.abstractThis review emphasises the importance of opioid monitoring in clinical practice and advocates for a personalised approach based on pharmacogenetics. Beyond effectively managing pain, meticulous oversight is required to address concerns about side effects, specially due to opioid-crisis-related abuse and dependence. Various monitoring techniques, along with pharmacogenetic considerations, are critical for personalising treatment and optimising pain relief while reducing misuse and addiction risks. Future perspectives reveal both opportunities and challenges, with advances in analytical technologies holding promise for increasing monitoring efficiency. The integration of pharmacogenetics has the potential to transform pain management by allowing for a precise prediction of drug responses. Nevertheless, challenges such as prominent pharmacogenetic testing and guideline standardisation persist. Collaborative efforts are critical for transforming scientific advances into tangible improvements in patient care. Standardised protocols and interdisciplinary collaboration are required to ensure consistent and evidence-based opioid monitoring. Future research should look into the long-term effects of opioid therapy, as well as the impact of genetic factors on individual responses, to help guide personalised treatment plans and reduce adverse events. Lastly, embracing innovation and collaboration can improve the standard of care in chronic pain management by striking a balance between pain relief and patient safety.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRosendo, L. M., Rosado, T., Zandonai, T., Rincon, K., Peiró, A. M., Barroso, M., & Gallardo, E. (2024). Opioid Monitoring in Clinical Settings: Strategies and Implications of Tailored Approaches for Therapy. International journal of molecular sciences, 25(11), 5925pt_PT
dc.identifier.doi10.3390/ijms25115925pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/51592
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationUIDP/00709/2020pt_PT
dc.relationHealth Sciences Research Centre
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectChronic painpt_PT
dc.subjectOpioidspt_PT
dc.subjectMonitoringpt_PT
dc.subjectPharmacogeneticspt_PT
dc.subjectClinical implicationspt_PT
dc.titleOpioid Monitoring in Clinical Settings: Strategies and Implications of Tailored Approaches for Therapypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleHealth Sciences Research Centre
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00709%2F2020/PT
oaire.citation.issue11pt_PT
oaire.citation.startPage5925pt_PT
oaire.citation.titleInternational Journal of Molecular Sciencespt_PT
oaire.citation.volume25pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameBarroso
person.givenNameMário
person.identifier.ciencia-id5110-F476-ECCC
person.identifier.orcid0000-0001-8848-2734
person.identifier.scopus-author-id35329243100
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication294b555e-48c4-4013-b981-b8917400c56c
relation.isAuthorOfPublication.latestForDiscovery294b555e-48c4-4013-b981-b8917400c56c
relation.isProjectOfPublication4ca3c3c9-1802-4c7f-8730-9547236896fe
relation.isProjectOfPublication.latestForDiscovery4ca3c3c9-1802-4c7f-8730-9547236896fe

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