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Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type

2024Journal article Open access
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dc.contributor.authorSilva, MI
dc.contributor.authorSantos, P
dc.contributor.authorViegas, D
dc.contributor.authorMiranda, M
dc.contributor.authorMontes, V
dc.contributor.authorPita, F
dc.contributor.authorCarmona, C
dc.date.accessioned2024-04-30T21:42:53Z
dc.date.available2024-04-30T21:42:53Z
dc.date.issued2024
dc.description.abstractNeurolymphomatosis (NL) describes an infiltration of cranial and peripheral nerves by lymphoma cells, most frequently in non-Hodgkin B-cell lymphoma. This clinical entity is rare and poses a challenging diagnosis. We describe a case of a 64-year-old female patient with NL associated with extra-nodal NK/T-cell lymphoma (ENKTL), nasal type, presenting as a painful progressive mononeuropathy multiplex with an oral cavity lesion. ENKTL is usually associated with Epstein-Barr virus (EBV) infection and rarely affects the central and peripheral nervous system. Lumbar puncture, magnetic resonance imaging (MRI), nerve biopsy, and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) help to establish the diagnosis. Thereby, NL should be considered in the differential diagnosis of painful progressive multiple neuropathies, even in patients without previous history of cancer.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationNeurol Sci . 2024 Mar 12. doi: 10.1007/s10072-024-07445-4.pt_PT
dc.identifier.doi10.1007/s10072-024-07445-4pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/50742
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectLinfoma Extranodal de Células T-NKpt_PT
dc.subjectNeurolinfomatosept_PT
dc.subjectLymphoma, Extranodal NK-T-Cellpt_PT
dc.subjectNeurolymphomatosispt_PT
dc.titleNeurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal typept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleNeurological Sciencespt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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