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Technology in Parkinson's disease: challenges and opportunities

dc.contributor.authorEspay, Alberto J., et al.
dc.contributor.authorMovement Disorders Society Task Force on Technology, on behalf of the
dc.date.accessioned2016-12-19T17:03:08Z
dc.date.available2017-10-01T00:30:11Z
dc.date.issued2016-09
dc.description.abstract"The miniaturization, sophistication, proliferation, and accessibility of technologies are enabling the capture of more and previously inaccessible phenomena in Parkinson's disease (PD). However, more information has not translated into a greater understanding of disease complexity to satisfy diagnostic and therapeutic needs. Challenges include noncompatible technology platforms, the need for wide-scale and long-term deployment of sensor technology (among vulnerable elderly patients in particular), and the gap between the “big data” acquired with sensitive measurement technologies and their limited clinical application. Major opportunities could be realized if new technologies are developed as part of open-source and/or open-hardware platforms that enable multichannel data capture sensitive to the broad range of motor and nonmotor problems that characterize PD and are adaptable into self-adjusting, individualized treatment delivery systems. The International Parkinson and Movement Disorders Society Task Force on Technology is entrusted to convene engineers, clinicians, researchers, and patients to promote the development of integrated measurement and closed-loop therapeutic systems with high patient adherence that also serve to (1) encourage the adoption of clinico-pathophysiologic phenotyping and early detection of critical disease milestones, (2) enhance the tailoring of symptomatic therapy, (3) improve subgroup targeting of patients for future testing of disease-modifying treatments, and (4) identify objective biomarkers to improve the longitudinal tracking of impairments in clinical care and research. This article summarizes the work carried out by the task force toward identifying challenges and opportunities in the development of technologies with potential for improving the clinical management and the quality of life of individuals with PD."pt_PT
dc.description.versioninfo:eu-repo/semantics/acceptedVersionpt_PT
dc.identifier.citationEspay, A. J., Bonato, P., Nahab, F. B., Maetzler, W., Dean, J. M., Klucken, J., Eskofier, B. M., Merola, A., Horak, F., Lang, A. E., Reilmann, R., Giuffrida, J., Nieuwboer, A., Horne, M., Little, M. A., Litvan, I., Simuni, T., Dorsey, E. R., Burack, M. A., Kubota, K., Kamondi, A., Godinho, C., Daneault, J.-F., Mitsi, G., Krinke, L., Hausdorff, J. M., Bloem, B. R., Papapetropoulos, S. and on behalf of the Movement Disorders Society Task Force on Technology (2016), Technology in Parkinson's disease: Challenges and opportunities. Mov Disord., 31: 1272–1282. doi:10.1002/mds.26642pt_PT
dc.identifier.doi10.1002/mds.26642pt_PT
dc.identifier.issn1531-8257
dc.identifier.urihttp://hdl.handle.net/10400.26/16919
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWileypt_PT
dc.relation.publisherversionhttp://onlinelibrary.wiley.com/doi/10.1002/mds.26642/abstractpt_PT
dc.subjectDigital healthpt_PT
dc.subjectDigital biomarkerspt_PT
dc.subjecteHealthpt_PT
dc.subjectParkinson’s diseasept_PT
dc.subjectPrecision medicinept_PT
dc.subjectRemote monitoringpt_PT
dc.subjectWearable technologypt_PT
dc.titleTechnology in Parkinson's disease: challenges and opportunitiespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1282pt_PT
oaire.citation.startPage1272pt_PT
oaire.citation.titleMovement Disorderspt_PT
oaire.citation.volume31(9)pt_PT
rcaap.embargofctPolítica de copyright da revistapt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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