| dc.contributor.author | Figueiredo, Sara | |
| dc.contributor.author | Pinto, João F. | |
| dc.contributor.author | Carvalho, Fátima G. | |
| dc.contributor.author | Fernandes, Ana Isabel | |
| dc.date.accessioned | 2022-05-18T11:03:31Z | |
| dc.date.available | 2022-05-18T11:03:31Z | |
| dc.date.issued | 2021 | |
| dc.description | Communication abstract: Proceedings of the 5th International Congress of CiiEM - Reducing inequalities in Health and Society, held at Egas Moniz’ University Campus in Monte de Caparica, Almada, from June 16th to 18th, 2021. | pt_PT |
| dc.description | This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | pt_PT |
| dc.description.abstract | This work reports the preliminary development of paroxetine-containing formulations amenable to hot-melt extrusion coupled to fused deposition modelling-based 3D printing. Polymeric matrices were used alone, or added with processing enhancers (e.g., plasticizer and filler). The polymeric formulation containing paroxetine (30% w/w), hydroxypropylcellulose (54% w/w) and excipients (16% w/w of dicalcium dihydrate phosphate, magnesium stearate and triethylcitrate; 10:1:5 ratio) exhibited the most suitable behaviour to be extruded and 3D printed, proving that adjuvants are critical to ensure processing of the formulations. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Figueiredo S, Pinto JF, Carvalho FG, Fernandes AI. Tuning of Paroxetine 3D-Printable Formulations for Fused Deposition Modelling. Medical Sciences Forum. 2021; 5(1):17. https://doi.org/10.3390/msf2021005017 | pt_PT |
| dc.identifier.doi | 10.3390/msf2021005017 | pt_PT |
| dc.identifier.isbn | 978-3-0365-2238-8 | |
| dc.identifier.isbn | 978-3-0365-2237-1 | |
| dc.identifier.issn | 2673-9992 | |
| dc.identifier.uri | http://hdl.handle.net/10400.26/40607 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | MDPI | pt_PT |
| dc.relation.publisherversion | https://doi.org/10.3390/msf2021005017 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Extrudability | pt_PT |
| dc.subject | Filament | pt_PT |
| dc.subject | Printability | pt_PT |
| dc.subject | 3D-printed tablet | pt_PT |
| dc.subject | Fused deposition modelling (FDM) | pt_PT |
| dc.subject | Hot melt extrusion (HME) | pt_PT |
| dc.subject | Paroxetine (PRX) | pt_PT |
| dc.title | Tuning of paroxetine 3D-printable formulations for fused deposition modelling | pt_PT |
| dc.type | other | |
| dspace.entity.type | Publication | |
| oaire.citation.startPage | 17 | pt_PT |
| oaire.citation.title | Medical Sciences Forum | pt_PT |
| oaire.citation.volume | 5(1) | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | other | pt_PT |
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