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Revisiting peri-implant soft tissue - histopathological study of the peri-implant soft tissue

dc.contributor.authorSilva, Eduarda
dc.contributor.authorFélix, Sérgio
dc.contributor.authorRodriguez-Archilla, Alberto
dc.contributor.authorOliveira, Pedro
dc.contributor.authorMartins dos Santos, José
dc.date.accessioned2015-03-27T16:55:57Z
dc.date.available2015-03-27T16:55:57Z
dc.date.issued2014-01
dc.descriptionReleased by the publisher under the “Creative Commons Attribution Non-Commercial License”, enabling the unrestricted non-commercial use, distribution, and reproduction of the published article in any medium, provided that the original work is properly cited.por
dc.description.abstract"Peri-implant soft tissues are essential for osseointegration. The peri-implant mucosa may lack vascular supply, and histological observation, even without plaque, shows the presence of inflammatory cells. The objectives of this study were to assess the histopathological changes of the epithelium and connective tissue around the implant. Twenty patients of both genders were studied. Twelve weeks after implant placement, fragments of peri-implant gingival sulcus were harvested and processed for light microscopy. Group I (10): without clinical inflammatory signs (control); Group II (10): with clinical inflammatory signs. Histopathological parameters were analyzed and classified in 3 grades: mild, moderate or severe (grade 1, 2 or 3). Control group showed only slight changes, grade 1. In group II we found edema with moderate to severe cellular and nuclear changes. There are more women than men with all grades of inflammation. All patients with moderate edema are male and all patients with severe edema are female. A significant association (p=0.007) exists between these two variables. Significant differences were found when comparing the degree of inflammation with nuclear alterations (p=0.001) and the same results when comparing the degree of edema and nuclear changes (p<0.001). This study demonstrates that clinical examination can be used, with a small margin of error, to monitor and control the state of the peri-implant mucosa. In clinics the predisposition of female patients to greater degree of edema and inflammation should be accounted for."por
dc.identifier.citationInt J Clin Exp Pathol. 2014; 7(2): 611–618.por
dc.identifier.issn1936-2625
dc.identifier.urihttp://hdl.handle.net/10400.26/8159
dc.language.isoengpor
dc.peerreviewedyespor
dc.publishere-Century Publishing Corporationpor
dc.relation.publisherversionwww.ijcep.compor
dc.relation.publisherversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925905/
dc.subjectPeri-implant soft tissuepor
dc.subjectHistopathological studypor
dc.subjectImplantpor
dc.subjectInflammationpor
dc.subjectGingivapor
dc.titleRevisiting peri-implant soft tissue - histopathological study of the peri-implant soft tissuepor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage618por
oaire.citation.startPage611por
oaire.citation.titleInternational Journal of Clinical and Experimental Pathologypor
oaire.citation.volume7(2)por
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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