Publication
Improving the identification of high-risk non-metastatic castration-resistant prostate cancer patients in clinical practice
dc.contributor.author | Rosinha, A | |
dc.contributor.author | Rabaça, C | |
dc.contributor.author | Calais, F | |
dc.contributor.author | Pinto, JM | |
dc.contributor.author | Barreira, JV | |
dc.contributor.author | Fernandes, R | |
dc.contributor.author | Ramos, R | |
dc.contributor.author | Fialho, AC | |
dc.contributor.author | Palma dos Reis, J | |
dc.date.accessioned | 2024-02-14T23:12:19Z | |
dc.date.available | 2024-02-14T23:12:19Z | |
dc.date.issued | 2024 | |
dc.description.abstract | Non-metastatic castration-resistant prostate cancer (nmCRPC) represents a challenging disease state in prostate cancer care. nmCRPC patients with a high risk of progression to metastatic disease who are identified by a prostate-specific antigen doubling time (PSADT) ≤10 months are eligible for treatment with the novel androgen receptor inhibitors (ARIs), shown to delay disease progression and extend survival. However, nmCRPC is often unexploited in clinical practice due to a lack of standardization in the methodology and in the tools used for its identification. In this article, a group of Urology and Oncology specialists with acknowledged expertise in prostate cancer reviews the state of the art in the management of high-risk nmCRPC patients, identifies gaps and unmet needs, and proposes strategies to optimize the identification of this patient subgroup in the clinical practice and improve their health outcomes. | pt_PT |
dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
dc.identifier.citation | Front Oncol . 2024 Jan 23:13:1266369. | pt_PT |
dc.identifier.doi | 10.3389/fonc.2023.1266369 | pt_PT |
dc.identifier.uri | http://hdl.handle.net/10400.26/49844 | |
dc.language.iso | eng | pt_PT |
dc.peerreviewed | yes | pt_PT |
dc.subject | Neoplasias de Próstata Resistentes à Castração | pt_PT |
dc.subject | Prostatic Neoplasms, Castration-Resistant | pt_PT |
dc.title | Improving the identification of high-risk non-metastatic castration-resistant prostate cancer patients in clinical practice | pt_PT |
dc.type | journal article | |
dspace.entity.type | Publication | |
oaire.citation.title | Frontiers in Oncology | pt_PT |
oaire.citation.volume | 13 | pt_PT |
rcaap.rights | openAccess | pt_PT |
rcaap.type | article | pt_PT |
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