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Efeito da fibrina rica em plaquetas (PRF) em diferentes procedimentos em implantologia : uma revisão sistemática
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| 4.05 MB | Adobe PDF |
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Abstract(s)
Introdução: A aplicação da fibrina rica em plaquetas em implantologia tem vindo a ser amplamente estudada nos últimos anos. Esta revisão sistemática apresenta a seguinte pergunta de pesquisa: A aplicação individual ou concomitante de PRF apresenta benefícios no campo da preservação alveolar, regeneração óssea, elevação do seio, estabilidade implantar, no tratamento da peri-implantite e na redução das complicações
pós-operatórias? Materiais e Métodos: Foi realizada uma pesquisa eletrónica em 4 bases de dados (PubMed, Web of Science, B-on e Scopus). A pesquisa foi realizada até o dia 21 de junho de 2021. Apenas foram incluídos para análise ensaios clínicos randomizados em inglês, português ou espanhol. Resultados: Como resultado da pesquisa foram obtidos 6814 artigos, dos quais apenas 52 foram incluídos para análise. A análise do risco de viés demonstrou que cerca de 27% dos artigos apresentaram baixo risco de viés, 29% risco
moderado e 44 % risco elevado. Discussão: Os protocolos de preparação, a seleção dos parâmetros clínicos e os períodos temporais em que os mesmos foram avaliados dificultam a real perceção dos benefícios do uso de PRF em implantologia. Conclusão: Apesar de alguns resultados promissores, não foi possível determinar a eficácia do PRF nos diferentes contextos em que é aplicado, sendo necessário a realização de estudos
clínicos controlados e randomizados adicionais. Relevância clínica: Apesar de não estar claro que o PRF apresenta resultados favoráveis quando aplicado isoladamente, é com certeza uma hipótese a ter em conta na hora de planear a reabilitação com implantes.
Introduction: The application of platelet-rich fibrin in implantology has recently been widely studied. This systematic review presents the following research question: Does the individual or concomitant application of PRF have benefits in the field of alveolar preservation, bone regeneration, sinus elevation, implant stability, in the treatment of peri-implantitis and in the reduction of post-operative complications? Materials and Methods: An electronic search was carried out in 4 databases (PubMed, Web of Science, B-on and Scopus). The survey was conducted until 21 of June of 2021. Only randomized clinical trials in english, portuguese or spanish were included for analysis. Results: As a result of the research, 6814 articles emerged, of which only 52 were included for analysis. The risk of bias showed about 27% of low risk, 29% of some concern and 44% of high risk. Discussion: The preparation protocols, the selection of clinical parameters and the time periods in which they were evaluated make it difficult to really measure the benefits of using PRF in implantology. Conclusion: It was not possible to determine the effectiveness of the PRF in the different contexts in which it was applied. Additional randomized controlled clinical trials are required. Clinical relevance: Although it is not clear that the PRF has favorable results when applied alone, it is certainly a hypothesis to consider when planning rehabilitation with implants.
Introduction: The application of platelet-rich fibrin in implantology has recently been widely studied. This systematic review presents the following research question: Does the individual or concomitant application of PRF have benefits in the field of alveolar preservation, bone regeneration, sinus elevation, implant stability, in the treatment of peri-implantitis and in the reduction of post-operative complications? Materials and Methods: An electronic search was carried out in 4 databases (PubMed, Web of Science, B-on and Scopus). The survey was conducted until 21 of June of 2021. Only randomized clinical trials in english, portuguese or spanish were included for analysis. Results: As a result of the research, 6814 articles emerged, of which only 52 were included for analysis. The risk of bias showed about 27% of low risk, 29% of some concern and 44% of high risk. Discussion: The preparation protocols, the selection of clinical parameters and the time periods in which they were evaluated make it difficult to really measure the benefits of using PRF in implantology. Conclusion: It was not possible to determine the effectiveness of the PRF in the different contexts in which it was applied. Additional randomized controlled clinical trials are required. Clinical relevance: Although it is not clear that the PRF has favorable results when applied alone, it is certainly a hypothesis to consider when planning rehabilitation with implants.
Description
Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas Moniz
Keywords
Fibrina rica em plaquetas Preservação alveolar Colocação de implante Regeneração óssea Elevação do seio maxilar Tratamento da peri-implantite