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Analysis of 10 X-linked tetranucleotide markers in mixed and isolated populations
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Orientador(es)
Resumo(s)
We have applied a recently described X-STRs decaplex to characterize four population groups of the Iberian Peninsula, including two well mixed populations and two relatively isolated ones from Northern Spain, in order to get a better insight about the characteristics of X-STRs in those population types between-population differences in allelic frequencies were relatively small. Nevertheless, Fst values were between 0.2 and 2.7%, figures higher than usually reported for autosomic STRs. This result suggests that when forensic cases originate from relatively isolated groups in western Europe, and a specific reference database is not available, it is probably safe to include a Fst-based correction in the calculations of matching or kinship probabilities.
Descrição
Palavras-chave
Genetics, Population Female Genetic Markers Genes, X-Linked
Contexto Educativo
Citação
Zarrabeitia, M. T., Pinheiro, F., de Pancorbo, M. M., Cainé, L., Cardoso, S., Gusmão, L., & Riancho, J. A. (2009). Analysis of 10 X-linked tetranucleotide markers in mixed and isolated populations. Forensic science international. Genetics, 3(2), 63–66. https://doi.org/10.1016/j.fsigen.2008.10.001
Editora
Elsevier