Repository logo
 
Publication

Entry inhibitors and Carbosilane dendrimers are potent inhibitors of cell-associated HIV-2 infection

2015-03-22Conference object Open access
Simple item page
dc.contributor.authorDiniz, A. R.
dc.contributor.authorBriz, V.
dc.contributor.authorBorrego, P.
dc.contributor.authorPalladino, C.
dc.contributor.authorRodés, C.
dc.contributor.authorDe la Mata, F. J.
dc.contributor.authorGómez, R.
dc.contributor.authorMuñoz-Fernández, M. A.
dc.contributor.authorTaveira, N.
dc.date.accessioned2016-10-12T14:07:14Z
dc.date.available2016-10-12T14:07:14Z
dc.date.issued2015-03-22
dc.descriptionPoster presented at the 2015 Keystone Symposia Conference X5: HIV Vaccines. Banff, Alberta, Canada, 22-27 March 2015pt_PT
dc.description.abstract"Pre-exposure prophylaxis with topical microbicides formulated with antiviral agents can prevent HIV-1 acquisition. The ideal microbicide should prevent both cell-free and cell-associated HIV-1 and HIV-2 infections in the vaginal or rectum mucosa. So far, few candidate microbicides have been tested against HIV-2. Previously, we have shown that anionic carbosilane dendrimers 2G-S16 (sulphonate), G2-NF16 (naphthylsulfonated) and G3-S16 (sulphated-end groups) have potent antiviral activity against HIV-1. In this work, we evaluated the activity of these dendrimers and the fusion inhibitors T-1249 and T20 in preventing cell-free and cellassociated HIV-2 infection."pt_PT
dc.description.sponsorshipFundação para a Ciência e a Tecnologia - Portugal; Fondo de Investigación Sanitaria through the Sara Borrell Programpt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/15088
dc.language.isoengpt_PT
dc.relationMolecular epidemiology, drug resistance and pathogenesis of HIV and TB in Angola: the Angolan PErinatal HIV Cohort (APEHC)
dc.relationDEVELOPMENT AND PRE-CLINICAL EVALUATION OF A NEW MICROBICIDE GEL FOR THE PREVENTION OF HIV-1 AND HIV-2 INFECTION
dc.subjectHIV-2 infectionpt_PT
dc.subjectEntry inhibitorspt_PT
dc.subjectCarbosilane dendrimerspt_PT
dc.titleEntry inhibitors and Carbosilane dendrimers are potent inhibitors of cell-associated HIV-2 infectionpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleMolecular epidemiology, drug resistance and pathogenesis of HIV and TB in Angola: the Angolan PErinatal HIV Cohort (APEHC)
oaire.awardTitleDEVELOPMENT AND PRE-CLINICAL EVALUATION OF A NEW MICROBICIDE GEL FOR THE PREVENTION OF HIV-1 AND HIV-2 INFECTION
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FSAU-EPI%2F122400%2F2010/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/VIH%2FSAU%2F0029%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F89140%2F2012/PT
oaire.citation.conferencePlaceBanff, Alberta, Canadapt_PT
oaire.citation.title2015 Keystone Symposia Conference X5: HIV Vaccinespt_PT
oaire.fundingStream3599-PPCDT
oaire.fundingStream3599-PPCDT
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isProjectOfPublicationc3b60260-41c1-4212-93cd-191d5b2e6133
relation.isProjectOfPublicatione63cde82-fa32-4aed-90e7-c9443427f2e1
relation.isProjectOfPublicationeb28382d-1ebf-4ed8-8974-0d1d07f67887
relation.isProjectOfPublication.latestForDiscoveryc3b60260-41c1-4212-93cd-191d5b2e6133

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Poster02_NTaveira_2015.pdf
Size:
186.71 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.85 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

EM - Posters