Segments HVS-I and HVS-II of mitochondrial DNA in a population from Santa Catarina (Brazil): Predominance of European lineages

Valverde, Laura; Palencia, Leire; Pinheiro, M. Fátima; Cainé, Laura; Cardoso, Sergio; Alfonso-Sánchez, Miguel A.; de Pancorbo, Marian M.

http://hdl.handle.net/10400.26/44363

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Authors

Alfonso-Sánchez, Miguel A.

de Pancorbo, Marian M.

Abstract(s)

The study of the hypervariable segments HVS-I and HVS-II of the mitochondrial DNA (mtDNA) control region of 80 healthy and maternally unrelated individuals revealed that the population from Santa Catarina is extremely heterogeneous, mainly due to the impact of relatively recent migratory waves from Europe. In spite of this, Native American lineages as well as African lineages incorporated much earlier are also present at noticeable proportions. This strikingly high variability generated by the intense gene flow is mirrored in a high power of discrimination (97.69%), which makes the analysis of mitochondrial HVS-I and HVS-II segments very useful for forensic genetic purposes in this Brazilian population.

Keywords

Genetics, Population Mitochondrial DNA Brazil Hipervariable segment

URI

http://hdl.handle.net/10400.26/44363

Citation

Valverde, L., Palencia, L., Pinheiro, M.F., Cardoso, S., Alfonso-Sánchez, M.A., de Pancorbo, M.M. Segments HVS-I and HVS-II of mitochondrial DNA in a population from Santa Catarina (Brazil): Predominance of European lineages. Forensic Science International: Genetics. Supplement Series, Volume 2, Issue 1. 2009. p. 338-339.