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Publication
Pancreatite em cães com babesiose
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Abstract(s)
A babesiose canina é causada por protozoários intraeritrocitários do género Babesia. Uma das suas possíveis complicações é a pancreatite, igualmente reportada como complicação em cães com Anemia Hemolítica Imunomediada (AHIM). No entanto, é pouco estudada a relação entre os processos hemolíticos agudos (de etiologia imunomediada ou não imunomediada) e a pancreatite. Os níveis séricos de lipase ácido éster 1,2-o-dilauril-rac-glicero-3-glutárico (DGGR), lipase 1,2-diglicerídeo (1,2-DiG), proteína C-reativa (CRP) e haptoglobina (Hp) foram avaliados em cães com babesiose da região centro de Portugal. A espécie mais prevalente foi B. canis, conforme verificado previamente na região norte do país. Os resultados obtidos, na determinação de lipase DGGR e lipase DiG, sugerem a ocorrência de pancreatite como complicação relativamente frequente da babesiose canina. Oito (21,6%) dos animais infetados apresentaram valores de lipase DGGR sugestivos de pancreatite. A CRP manifestou ser um biomarcador muito sensível de babesiose. De acordo com os resultados obtidos, deve-se suspeitar de pancreatite nos animais infetados por Babesia spp., principalmente na presença de hemólise moderada a grave.
Canine babesiosis is caused by intraerythrocytic protozoa of Babesia spp. One of its possible complications is pancreatitis, also reported as a complication in dogs with Immunomediated Hemolytic anemia (IMHA). However, the relationship between acute hemolytic processes (whether immuno- mediated or not) and pancreatitis is scarcely studied. Serum lipase 1,2–o-dilauryl-rac-glycero-3-glutaric acid ester (DGGR), lipase 1,2-diglyceride (1,2 DiG), C-reactive protein (CRP) and haptoglobin (Hp) were evaluated in dogs with babesiosis from central Portugal. The most prevalent species was B. canis, as previously observed in northern Portugal. The results obtained in the determination of lipase DGGR and lipase DiG suggest the occurrence of pancreatitis as a relatively common complication of canine babesiosis. Eight dogs (21,6%) out of the 37 infected animals presented serum levels of lipase DGGR compatible with pancreatitis. C-reactive protein proved to be a biomarker with high sensitivity in babesiosis. According to the results obtained, pancreatitis should be suspected in animals infected with Babesia spp., especially in the presence of moderate to severe hemolysis.
Canine babesiosis is caused by intraerythrocytic protozoa of Babesia spp. One of its possible complications is pancreatitis, also reported as a complication in dogs with Immunomediated Hemolytic anemia (IMHA). However, the relationship between acute hemolytic processes (whether immuno- mediated or not) and pancreatitis is scarcely studied. Serum lipase 1,2–o-dilauryl-rac-glycero-3-glutaric acid ester (DGGR), lipase 1,2-diglyceride (1,2 DiG), C-reactive protein (CRP) and haptoglobin (Hp) were evaluated in dogs with babesiosis from central Portugal. The most prevalent species was B. canis, as previously observed in northern Portugal. The results obtained in the determination of lipase DGGR and lipase DiG suggest the occurrence of pancreatitis as a relatively common complication of canine babesiosis. Eight dogs (21,6%) out of the 37 infected animals presented serum levels of lipase DGGR compatible with pancreatitis. C-reactive protein proved to be a biomarker with high sensitivity in babesiosis. According to the results obtained, pancreatitis should be suspected in animals infected with Babesia spp., especially in the presence of moderate to severe hemolysis.
Description
Keywords
Anemia hemolítica Babesiose Hemólise Lipase DGGR Lipase DiG Pancreatite Babesiosis Hemolysis Hemolytic anemia Pancreatitis