Publication
Efeito do uso de probiĆ³ticos na fase higiĆ©nica do tratamento da peri-implantite
| dc.contributor.advisor | Santos, Alexandre Miguel | |
| dc.contributor.author | Medeiros, Mafalda de Oliveira Neves Bettencourt de | |
| dc.date.accessioned | 2021-12-23T10:26:29Z | |
| dc.date.available | 2021-12-23T10:26:29Z | |
| dc.date.issued | 2021-10 | |
| dc.description | DissertaĆ§Ć£o para obtenĆ§Ć£o do grau de Mestre no Instituto UniversitĆ”rio Egas Moniz | pt_PT |
| dc.description.abstract | IntroduĆ§Ć£o: Segundo a nova classificaĆ§Ć£o de 2017, a peri-implantite Ć© uma condiĆ§Ć£o patolĆ³gica inflamatĆ³ria associada Ć placa bacteriana ao redor dos implantes dentĆ”rios e com a perda progressiva do osso de suporte. Uma vez que o tratamento nĆ£o-cirĆŗrgico Ć© pouco eficaz no tratamento da peri-implantite, novas abordagens terapĆŖuticas estĆ£o a ser estudadas, entre elas o uso de probiĆ³ticos, que dependendo da dose administrada poderĆ£o ser benĆ©ficos para o hospedeiro. Objetivo: O principal objetivo desta revisĆ£o Ć©, atravĆ©s de evidĆŖncia cientĆfica atual, avaliar se existe algum benefĆcio no uso de probiĆ³ticos como abordagem terapĆŖutica nĆ£o-cirĆŗrgica no tratamento da peri-implantite. Materiais e MĆ©todos: A pergunta de pesquisa (PICO) Ć© entĆ£o formulada e os critĆ©rios de inclusĆ£o e exclusĆ£o definidos apartir da mesma. Foram incluĆdos estudos de lĆngua portuguesa, inglesa e espanhola, em que tenham sido administrados probiĆ³ticos em pacientes com peri-implantite. Para a exclusĆ£o de estudos os critĆ©rios usados foram a utilizaĆ§Ć£o de antimicrobianos antes do tratamento da peri-implantite e estudos que nĆ£o fossem ensaios clĆnicos. As bases de dados eletrĆ³nicas PubMed, Web of Science, Scopus e B-on foram analisadas atĆ© 27 de maio de 2021 e os estudos selecionados foram sujeitos ao Rob 2, para determinar o risco de viĆ©s. Resultados: Da anĆ”lise de 135 resumos e tĆtulos foram selecionados 8 artigos para leitura integral, dos quais somente 3 artigos foram incluĆdos nesta revisĆ£o sistemĆ”tica. Todos os estudos mostraram reduĆ§Ć£o significativa em algum dos parĆ¢metros clĆnicos (Dois na PS p<0.05 e p<0.05; Um no IPI p<0.002; Dois no HSI p<0.045 e p<0.001, e um nas amostras microbiolĆ³gicas p<0.001 e p<0.040). A elevada heterogeneidade metodolĆ³gica dos estudos incluĆdos poderĆ” influenciar os resultados obtidos. ConclusĆ£o: De modo geral os probiĆ³ticos ajudam na melhoria dos sinais clĆnicos da doenƧa, mas sĆ£o necessĆ”rios mais ensaios clĆnicos, com nĆŗmero de indivĆduos e perĆodos de follow-up maiores. | pt_PT |
| dc.description.abstract | Introduction: According to the new 2017 classification, peri-implantitis is an inflammatory pathological condition associated with bacterial plaque that occurs around dental implants and with the progressive loss of supporting bone. Since non-surgical treatment show low effectiveness in the treatment of peri-implantitis, new therapeutic approaches are being studied, including the use of probiotics, which, depending on the administered dose, can provide benefits to the host. Objective: The main objective of this work is through current scientific evidence, know if there is any benefit in the use of probiotics as a non-surgical approach in the treatment of peri-implantitis. Materials and Methods: The research question (PICO) is then formulated and the inclusion and exclusion criteria defined from it. Studies written in Portuguese, English and Spanish were included, in which probiotics were administered in patients with peri-implantitis. For the exclusion of studies, the criteria used were the use of antimicrobials before the treatment of peri-implantitis and studies that were not clinical trials. The electronic databases PubMed, Web of Science, Scopus and B-on were analyzed until May 27, 2021 and selected studies were subjected to Rob 2 to determine the risk of bias. Results: From the analysis of 135 abstracts and titles, 8 articles were selected for full reading, of which only 3 articles were included in this systematic review. All studies showed a significant reduction in some of the clinical parameters (Two in PS p<0.05 and p<0.05; One in IPI p<0.002; Two in HSI p<0.045 and p<0.001, and one in microbiological samples p<0.001 and p<0.040). The high methodological heterogeneity of the included studies may be affecting the results obtained Conclusion: In general, probiotics improve clinical signs of the disease, but more clinical trials are needed, with a longer number of subjects and longer follow-up periods. | pt_PT |
| dc.identifier.tid | 202814360 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.26/38451 | |
| dc.language.iso | por | pt_PT |
| dc.subject | ProbiĆ³ticos | pt_PT |
| dc.subject | Lactobacillus | pt_PT |
| dc.subject | Peri-implantite | pt_PT |
| dc.subject | Tratamento da peri-implantite | pt_PT |
| dc.title | Efeito do uso de probiĆ³ticos na fase higiĆ©nica do tratamento da peri-implantite | pt_PT |
| dc.type | master thesis | |
| dspace.entity.type | Publication | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | masterThesis | pt_PT |
| thesis.degree.name | Mestrado Integrado em Medicina DentƔria | pt_PT |
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