Repository logo
 
Publication

Parámetros hematológicos descuidados en el pronóstico de la insuficiencia cardíaca-Evidencia del estudio REFERENCE

2022Journal article Open access
Simple item page
dc.contributor.authorBarbosa, M
dc.contributor.authorMatos, A
dc.contributor.authorBicho, M
dc.contributor.authorFalcão, LM
dc.date.accessioned2022-09-04T21:06:26Z
dc.date.available2022-09-04T21:06:26Z
dc.date.issued2022
dc.description.abstractAims: In heart failure patients, anemia and iron deficiency are predictors of poor outcome. We studied the association of anemia, iron deficiency and related hematological parameters with short-term rehospitalization, short-term all-cause mortality and end of follow-up all-cause mortality in heart failure patients. Material and Methods: Anemia, iron deficiency, red cell distribution width and erythropoietin were assessed in patients hospitalized with acute decompensated heart failure. Univariate Cox proportional hazard model was used to assess the relationship between variables and outcomes. Results: 65 patients were followed for a median of 13.7 (Q1-Q3 6.7-18.9) months. Mean age was 79.2 (SD 10.8) years. The mean left ventricular ejection fraction was 50.38 ± 19.07 %. Variables associated with an increased risk for short-term rehospitalization were red cell distribution width (HR 1.35; 95% CI 1.16- 1.58), anemia (HR 3.81; 95% CI 1.29-11.28) and anemia with iron deficiency (HR 3.50; 95% CI 1.30-9.38). Increased risk for short-term mortality was associated with red cell distribution width (HR 1.83; 95% CI 1.29-2.59), erythropoietin (HR 1.38; 95% CI 1.04-1.82), absolute iron deficiency (HR 7.22; 95% CI 1.50-34.81) and anemia with iron deficiency (HR 4.48; 95% CI 1.26-15.88). Variables associated with increased risk for end of follow-up mortality were red cell distribution width (HR 1.31; 95% CI 1.12-1.54) and erythropoietin (HR 1.29; 95% CI 1.11-1.49). Conclusions: Conclusions: Anemia and red cell distribution width correlated with higher risk for short-term rehospitalization. Absolute iron deficiency, red cell distribution width and erythropoietin were associated with higher risk for short-term mortality. Red cell distribution width and erythropoietin were associated with higher risk for end of follow-up mortality.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationGalicia Clin 2022; 83-2: 20-31pt_PT
dc.identifier.doi10.22546/65/2413pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/41715
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectInsuficiência Cardíacapt_PT
dc.subjectTestes Hematológicospt_PT
dc.subjectAnemia/complicaçõespt_PT
dc.subjectAnemia Ferropénica/complicaçõespt_PT
dc.subjectAnemia/complicationspt_PT
dc.subjectHeart Failurept_PT
dc.subjectHematologic Testspt_PT
dc.subjectAnemia, Iron-Deficiency/complicationspt_PT
dc.titleParámetros hematológicos descuidados en el pronóstico de la insuficiencia cardíaca-Evidencia del estudio REFERENCEpt_PT
dc.title.alternativeNeglected hematological parameters in heart failure prognosis – Disclosures from the REFERENCE studypt_PT
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Neglected hematological parameters in heart failure prognosis – Disclosures from the REFERENCE study.pdf
Size:
569.61 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.85 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

LS - LHL - Artigos