Development of casein micellar pediatric formulations

Brachkova, M. I.; Pinto, J. T.; Fernandes, A. I.; Pinto, J. F.

Publication

Development of casein micellar pediatric formulations

2015-04-13Conference object

dc.contributor.author	Brachkova, M. I.
dc.contributor.author	Pinto, J. T.
dc.contributor.author	Fernandes, A. I.
dc.contributor.author	Pinto, J. F.
dc.date.accessioned	2016-04-29T14:04:53Z
dc.date.available	2016-04-29T14:04:53Z
dc.date.issued	2015-04-13
dc.description	Poster presented at the 1st European Conference on Pharmaceutics. 13-14 April 2015, Reims, France.	pt_PT
dc.description.abstract	"The current need for medicines specifically designed for children, which consider ease of administration, dose flexibility, palatability, safety of excipients, stability and therapeutic equivalency of pediatric dosage forms, has driven the development of pediatric drug formulations. In the present work casein (CN) based micellar formulations are evaluated as vehicles for the oral delivery of pediatric drugs, since caseins are nontoxic, biodegradable, GRAS materials and nanoencapsulation of drugs can improve their bioavailability. Chemical crosslinking of casein by carbodiimide (EDC) has been studied as an approach to improve the stability of the CN micelles and to tailor drug release."	pt_PT
dc.description.sponsorship	Fundação para a Ciência e a Tecnologia, Portugal (Research grant PTDC/DTPFTO/1057/2012)	pt_PT
dc.identifier.uri	http://hdl.handle.net/10400.26/13398
dc.language.iso	eng	pt_PT
dc.relation	Powdered medicinal milks for oral delivery of drugs in paediatrics (MedMilk)
dc.subject	Casein	pt_PT
dc.subject	Micellar formulations	pt_PT
dc.subject	Pediatric drugs	pt_PT
dc.title	Development of casein micellar pediatric formulations	pt_PT
dc.type	conference object
dspace.entity.type	Publication
oaire.awardTitle	Powdered medicinal milks for oral delivery of drugs in paediatrics (MedMilk)
oaire.awardURI	info:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FDTP-FTO%2F1057%2F2012/PT
oaire.citation.conferencePlace	Reims, France	pt_PT
oaire.citation.title	1st European Conference on Pharmaceutics	pt_PT
oaire.fundingStream	3599-PPCDT
project.funder.identifier	http://doi.org/10.13039/501100001871
project.funder.name	Fundação para a Ciência e a Tecnologia
rcaap.rights	openAccess	pt_PT
rcaap.type	conferenceObject	pt_PT
relation.isProjectOfPublication	a0df4380-9007-4eab-b38d-fd36fc6745f6
relation.isProjectOfPublication.latestForDiscovery	a0df4380-9007-4eab-b38d-fd36fc6745f6