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Sex cord-stromal tumours of the ovary: a comprehensive update review

dc.contributor.authorHorta, Mariana
dc.contributor.authorCunha, Teresa Margarida
dc.date.accessioned2016-10-03T11:11:26Z
dc.date.available2016-10-03T11:11:26Z
dc.date.issued2015
dc.date.updated2016-07-23T11:09:02Z
dc.description.abstractOvarian sex cord-stromal tumors are infrequent and represent approximately 7% of all primary ovarian tumors. This histopathologic ovarian tumor group differs considerably from the more prevalent epithelial ovarian tumors. Although sex cord-stromal tumors present in a broad age group, the majority tend to present as a low-grade disease that usually follows a nonaggressive clinical course in younger patients. Furthermore, because the constituent cells of these tumors are engaged in ovarian steroid hormone production (e.g., androgens, estrogens, and corticoids), sex cord-stromal tumors are commonly associated with various hormone-mediated syndromes and exhibit a wide spectrum of clinical features ranging from hyperandrogenic virilizing states to hyperestrogenic manifestations. The World Health Organization sex cord-stromal tumor classification has recently been revised, and currently these tumors have been regrouped into the following clinicopathologic entities: pure stromal tumors, pure sex cord tumors, and mixed sex cord-stromal tumors. Moreover, some entities considered in the former classification (e.g., stromal luteoma, stromal tumor with minor sex cord elements, and gynandroblastoma) are no longer considered separate tumors in the current classification. Herein, we discuss and revise the ultrasonography, computed tomography, and magnetic resonance imaging characteristics of the different histopathologic types and clinicopathologic features of sex cord-stromal tumors to allow radiologists to narrow the differential diagnosis when facing ovarian tumors.pt_PT
dc.identifier1305-3825en_US
dc.identifier.citationMariana Horta; Teresa Margarida Cunha. Sex Cord-stromal Tumours of the Ovary: a Comprehensive Update Review, Diagnostic and Interventional Radiology, 21, 4, 277-286, 2015.pt_PT
dc.identifier.issn1305-3825
dc.identifier.urihttp://hdl.handle.net/10400.26/14935
dc.language.isoengpt_PT
dc.titleSex cord-stromal tumours of the ovary: a comprehensive update reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage286pt_PT
oaire.citation.startPage277pt_PT
oaire.citation.titleDiagnostic and Interventional Imagingpt_PT
oaire.citation.volume21pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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