Publication
Determination of Antiepileptics in Biological Samples—A Review
| dc.contributor.author | Martinho, João | |
| dc.contributor.author | Simão, Ana Y. | |
| dc.contributor.author | Barroso, Mário | |
| dc.contributor.author | Gallardo, Eugenia | |
| dc.contributor.author | Rosado, Tiago | |
| dc.date.accessioned | 2025-01-27T10:00:34Z | |
| dc.date.available | 2025-01-27T10:00:34Z | |
| dc.date.issued | 2024 | |
| dc.description.abstract | Epilepsy remains a disease that affects many people around the world. With the development of new drugs to treat this condition, the importance of therapeutic drug monitoring continues to rise and remains a challenge for the medical community. This review article explores recent advances in the detection of antiepileptic drugs across various sample types commonly used for drug monitoring, with a focus on their applications and impact. Some of these new methods have proven to be simpler, greener, and faster, making them easier to apply in the context of therapeutic drug monitoring. Additionally, besides the classic use of blood and its derivatives, there has been significant research into the application of alternative matrices due to their ease of sample collection and capacity to reflect drug behavior in blood. These advances have contributed to increasing the efficacy of therapeutic drug monitoring while enhancing its accessibility to the population. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Martinho, J., Simão, A. Y., Barroso, M., Gallardo, E., & Rosado, T. (2024). Determination of Antiepileptics in Biological Samples-A Review. Molecules (Basel, Switzerland), 29(19), 4679 | pt_PT |
| dc.identifier.doi | 10.3390/molecules29194679 | pt_PT |
| dc.identifier.issn | 1420-3049 | |
| dc.identifier.uri | http://hdl.handle.net/10400.26/54002 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | MDPI | pt_PT |
| dc.relation | Health Sciences Research Centre | |
| dc.relation | Health Sciences Research Centre | |
| dc.relation | Hair as a monitoring tool for new drugs: synthetic cannabinoids and opioids | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Antiepileptic drugs | pt_PT |
| dc.subject | Blood and derivates | pt_PT |
| dc.subject | Exhaled air | pt_PT |
| dc.subject | Hair | pt_PT |
| dc.subject | Monitoring | pt_PT |
| dc.subject | Saliva | pt_PT |
| dc.subject | Urine | pt_PT |
| dc.title | Determination of Antiepileptics in Biological Samples—A Review | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | Health Sciences Research Centre | |
| oaire.awardTitle | Health Sciences Research Centre | |
| oaire.awardTitle | Hair as a monitoring tool for new drugs: synthetic cannabinoids and opioids | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00709%2F2020/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00709%2F2020/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/PDQI_CENTRO/2020.09070.BD/PT | |
| oaire.citation.conferencePlace | Basel, Switzerland | pt_PT |
| oaire.citation.issue | 19 | pt_PT |
| oaire.citation.startPage | 4679 | pt_PT |
| oaire.citation.title | Molecules | pt_PT |
| oaire.citation.volume | 29 | pt_PT |
| oaire.fundingStream | 6817 - DCRRNI ID | |
| oaire.fundingStream | 6817 - DCRRNI ID | |
| oaire.fundingStream | PDQI_CENTRO | |
| person.familyName | Barroso | |
| person.givenName | Mário | |
| person.identifier.ciencia-id | 5110-F476-ECCC | |
| person.identifier.orcid | 0000-0001-8848-2734 | |
| person.identifier.scopus-author-id | 35329243100 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
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