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  • Overview of bioremediation with technology assessment and emphasis on T fungal bioremediation of oil contaminated soils
    Publication . Quintella, Cristina; Mata, A. M. T.; Lima, Leandro
    Environmental contamination is a problem that requires sustainable solutions. Bioremediation technologies have been developed in the last decades and are increasingly used to mitigate environmental accidents and systematic contaminations. A review of bioremediation technologies, based on published article and patent documents, is presented for different types of contaminated matrices, bioremediation agents and contaminants. The worldwide database of the European Patent Office was searched using radicals of keyword as well as the International Patent Classification (IPC) to identify patents in our areas of concern. Technological domains, annual filing volume, legal status, assignee countries and development collaborations are presented and examples are dis- cussed. The total number of patents is compared with the total number of articles. A SWOT analysis for bior- emediation technologies is presented. The technologies for water (53%), soils (36%), and sludges (11%) are growing yearly at nearly constant rates. The bioremediation agents are predominantly bacteria (57%), enzymes (19%), fungi (13%), algae (6%), plants (4%) and protozoa. The major contaminants are oils (38%), followed by metals (21%), organic waste (21%), polymers (10%), food (5%), cellulose (5%) and biodiesel. Most of the patents are generally originated from China and United States of America. The soils bioremediation technology of oil is centered on bacteria usage (about two thirds of the articles and patents), being fungi a technology with critical mass and high growth potential. A recent trend in oil bioremediation of soils is the combination of bioremediation agents (fungi and bacteria) in the same process, thus making the process more robust to en- vironment changes.
  • Vacinas para Coronavírus (COVID-19; SARS- COV-2): mapeamento preliminar de artigos, patentes, testes clínicos e mercado
    Publication . Quintella, Cristina; Mata, A. M. T.; Ghesti, Grace; Mata, Pedro
    O recente surto de Coronavírus gerou uma pandemia mundial. Este artigo consiste em um estudo exploratório para avaliar parcialmente o volume existente de material e o potencial de aprofundar futuras prospecções tecnológicas. O propósito deste estudo é o de pré-avaliar o conhecimento que existe em ciência (por meio de artigos), em tecnologia (por meio de patentes) e em testes clínicos e prontos para uso (por meio de vacinas disponíveis no mercado). Os artigos foram mapeados na Web of Knowledge, o mapeamento patentário usou a base Worldwide europeia, usando o software Orbit®. Os estudos clínicos utilizaram a base de dados dos Estados Unidos da América (EUA). Foram encontradas 991 patentes, 125 artigos e 115 estudos clínicos sendo apenas dois que se referem explicitamente a vacinas. A evolução anual mostra um crescimento exponencial a partir de 2002-2004 para artigos e para patentes. A grande maioria dos estudos clínicos nem foi ainda iniciada (apenas 15% foram completados), evidenciando que há necessidade urgente de estimular sua maturação. Não existe, no momento, no mercado, uma vacina que seja considerada efetiva mundialmente.