Browsing by resource type "working paper"
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- A ambiguidade da(s) narrativa(s) de Obama sobre o uso da forçaPublication . Saraiva, FranciscaO texto aborda a retórica presidencial de Obama em relação ao papel da força armada na política externa americana a partir das narrativas de segurança nacional construída pelas elites nacionais. Argumenta-se que a cultura estratégica norte-americana do pós- Guerra Fria tem estado ligada a uma narrativa de declínio do poder internacional dos Estados Unidos, construída nacionalmente, e crescentemente a uma narrativa secundária, a narrativa do caos terrorista. A consequência mais imediata das ambiguidades da Administração Obama, que promove a paz e faz a guerra (justa), é a possibilidade de consolidação da teoria do declínio e a institucionalização e normalização da guerra contra o terrorismo como nova ameaça à cultura estratégica dos Estados Unidos.
- Bechcet´s Disease : an old illness with a new treatment?Publication . Perneta, Filipe; Caldeira, Mónica; Chaves, Susana; Jardim, Margarida; Miranda, Rubina; Câmara, Margarida; Reis, Maria da Luz
- Cibersegurança: das preocupações à açãoPublication . Caldas, Alexandre; Freire, Vicente
- Didática em enfermagem: documento orientador de processos de ensino e aprendizagemPublication . Cerqueira, Andreia Filomena Ferreri de Gusmão Gonçalves; Marques, Fernanda Maria Gomes da Costa Teixeira; Leal, Paula; Nunes, Lucília
- Distal mummification of all limbs-an odd presentation of multiple myelomaPublication . Pestana, A; Gomes, C; Correia, M.I.; Capelo, M; Freitas, P; Jacinto, F; Brazão, Maria Da Luz
- Estudo do desperdício alimentar e do grau de satisfação existente no serviço de ortopedia do HNM do SESARAM, EPE.Publication . Alves, Rogério; Coutinho, Maria Moisés; Caldeira, Ana Paula Bettencourt; Teixeira, Maria Amélia Fernandes; Castro, Maria Manuela
- EU-NATO Cooperation: report of the international conference organized at the National Defence Institut (IDN) on 15 February 2021Publication . Nunes, Isabel Ferreira; Daehnhardt, Patrícia; Seabra, Pedro; Costa, Rita
- Exploring Digital Accounting Challenges at Vila do Conde City CouncilPublication . Sousa, Cristiana; Oliveira, Helena Costa; Maldonado, IsabelThe advancement of information technologies in the digital age has significantly impacted human activity and various professional fields, becoming increasingly prevalent in society. Over time, technology has profoundly transformed public accounting, enabling more efficient, effective, and optimized practices. Innovative tools, such as blockchain, artificial intelligence, and cloud computing, have emerged as key drivers of this evolution. This paper aims to analyze the impact of information technologies on the accounting practices of the Vila do Conde City Council, in Portugal. The study identifies the technological systems and the changes due to the Accounting Standardization System for Public Administrations (SNC-AP) and explores the advantages and challenges of these technologies. This qualitative research method uses interviews and documentary analysis. The findings reveal that while the council has already implemented systems such as Enterprise Resource Planning, there are opportunities to introduce more advanced accounting technologies. Issues such as budgetary constraints and cultural resistance to change influence the pace of technological implementation. However, the council has taken a proactive approach in other areas, focusing on service digitalization and community engagement. This study provides a valuable reference for other public entities looking to modernize their processes and enhance community services. Identifying challenges and barriers in implementing technology enables public administrations to anticipate issues and implement effective solutions.
- Exploring the potential of a MEPS/UHPLC-based methodology on the Exploring the potential of a MEPS/UHPLC-based methodology on thePublication . Berenguer, Pedro; Camacho, Irene C; Câmara, José S.; Câmara, Rita; Oliveira, SusanaAsthma is a heterogeneous disease characterized by chronic inflammation and long term irreversible remodeling of the airways. The enzymatic peroxidation of the arachidonic acid is part of the pathophysiology of this disease and leads to the formation of powerful inflammatory mediators, characteristic of asthma. The present work aimed to develop an easy-to-use ultra-high pressure liquid chromatography (UHPLC)-based strategy in order to characterize lipid peroxidation biomarkers: leukotrienes E4 (LTE4) and B4 (LTB4) and 11β-prostaglandin F2α (11βPGF2α), eicosanoids present in the urine of asthmatic patients and healthy individuals (control group). A semi-automatic eVol®-microextraction by packed sorbent (MEPS) format was developed in order to isolate the target analytes. The method was fully validated under optimal extraction (R-AX sorbent, 3 conditioning-equilibration cycles with 250 μL of ACN-H2O at 0.1% FA, 10 extract-discard cycles of 250 μL of sample at a pH of 5.1, elution with 2 times 50 μL of MeOH and concentration of the eluate until half of its volume) and chromatographic conditions (14-min analysis at a flow rate of 300 μL min-1 in an UHPLCPDA equipped with a BEH C18 column). Our results indicated good recoveries (>95%) in addition to excellent extraction efficiency (>95%) at three concentration levels (low, mid and high) with precision (RSDs) less than 11%. The lack-of-fit, goodness-of-fit and Mandel’s fitting tests, revealed good linearity within the concentration range. Good selectivity and sensitivity were achieved with limits of detection ranging from 0.04 ng mL-1 for LTB4 to 1.12 ng mL-1 for 11βPGF2α, and limits of quantification from 0.10 ng mL- 1 for the LTB4 to 2.11 ng mL-1 for 11βPGF2α. The developed method was successfully applied to the urine of asthmatic patients and healthy individuals. On average, the urine of asthmatic patients present significantly higher concentrations of 11βPGF2α (112.96 ng mL-1 vs 62.56 ng mL-1 in control group), LTE4 (1.27 ng mL-1 vs 0.89 ng mL-1 in control group) and LTB4 (1.39 ng mL-1 vs 0.76 ng mL- 1 in control group). These results suggest the potential of the target eicosanoids and the developed method on asthma diagnosis and on the follow-up of the therapeutic response.