Browsing by Issue Date, starting with "2021-05-27"
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- PAUSA - Projeto de reabilitaçãoPublication . Pereira, Maria; Cruz, JoãoNos últimos anos a arquitectura tem se baseado na estratégia de persuasão através da publicidade, como meio a atingir o desejo de um impacto instantâneo, resultando de uma perda de temporalidade, reforçadas pelo enfraquecimento da materialidade. Deste modo, defende-se neste trabalho a importância de manter os materiais primitivos. como a pedra ou a madeira que nos revertem para a realidade da matéria, que nos contam as suas origens e histórias, que nos fazem viajar e nos ligam a uma beleza natural, criando assim um projeto de restauração inserido no Clube de ténis de Guimarães, em que o interior e o exterior estão sempre intrinsecamente conectados.
- Evolução de Custos Medicamentos inovadores - ResultadosPublication . Garcia, Martinha; Vieira, Ana Paula
- Cytomegalovirus Pulmonary Involvement in an Immunocompetent AdultPublication . Luís, Helena; Barros, Carolina; Gomes, Mariana; Andrade, José Luís; Faria, NancyCytomegalovirus (CMV) is a linear double-stranded DNA virus that may cause severe and potentially fatal infection in immunocompromised hosts. In immunocompetent individuals, the infection is typically mild or asymptomatic. However, in the last years, some cases of severe cytomegalovirus infection in immunocompetent individuals have been described. Clinical Presentation. 'e authors present a male patient aged 42 years, without specific medical history, who presented a 15-day history of fever, headache, night sweats, odynophagia, and bilateral otalgia, without improvement after four days of therapy with amoxicillin/clavulanic acid. Blood count and biochemistry were performed with liver cytolysis pattern. Chest teleradiography showed diffuse interstitial infiltrate. 'oracic CT scan revealed areas in a ground glass with a cross-linking component in the left and right upper lung lobes compatible with an inflammatory/infectious process. Blood serology was positive for CMV IgG and IgM. 'e detection on blood and bronchoalveolar lavage of CMV DNA by polymerase chain reaction (PCR) was also positive. Ganciclovir was started based on the clinical features and the result of CMV serology. After 48 hours, there was a significant clinical improvement, with remission of fever, and he was discharged on the 13th day of hospitalization with oral valganciclovir, completing a 21-day antiviral course at home. Conclusion. With this clinical case, the authors highlight the importance of considering CMV infection in evaluating patients with pneumonia, even in immunocompetent ones, particularly in those with no clinical improvement with antibiotics instituted for bacterial pneumonia, and when other causes have been ruled out