Browsing by Issue Date, starting with "2016-04-01"
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- Thrombolysis in Patients Aged over 80 Years Is Equally Effective and SafePublication . Pego, PM; Nunes, AP; Ferreira, P; Sousa, C; Amaral-Silva, ABACKGROUND: Despite stroke's high prevalence in the elderly, intravenous thrombolysis is licensed in Europe only for patients younger than 80 years old. We aimed to compare the functional outcomes and complication rates in patients older versus younger than 80 years old treated with intravenous thrombolysis. METHODS: A retrospective observational study of patients who received intravenous thrombolysis in a stroke unit between January 1, 2009, and June 30, 2012, was conducted. Variables were compared between 2 subgroups (≤80 and >80 years). RESULTS: Overall, 512 patients underwent intravenous thrombolysis, of which 13.1% were over 80 years. The mean age was 65.4 years in the younger subgroup and 82.9 years in the older subgroup. Prior independence rates did not differ between the subgroups. Prevalence of atrial fibrillation and cardioembolic stroke was higher in the older subgroup (P = .004 and .026). Only 3% of the elderly with atrial fibrillation were taking oral anticoagulants. Symptoms-to-needle time was lower in the older subgroup (P = .048). Stroke severity was higher in patients over 80 years (P = .026). There was significant improvement in the National Institutes of Health Stroke Scale score 7 days after intravenous thrombolysis (P < .001) in both subgroups. The proportion of patients with 3 months' favorable outcome and independence, hemorrhagic transformation, and mortality rates were similar in both subgroups. CONCLUSIONS: Elderly patients' benefits and outcomes from intravenous thrombolysis treatment were identical to the younger subgroup without excess hemorrhagic transformation or mortality. These results favor the use of intravenous thrombolysis in patients over 80 years.
- O desenvolvimento das competências de literacia nos idosos e a promoção da autoestima : estudo com idosos numa academia séniorPublication . Careira, Sílvia de Fátima Catambas; Martins, Alexandre Miguel Cotovio de SáO presente estudo diz respeito a um estudo de caso que relaciona entre si alguns conceitos fundamentais: envelhecimento ativo; aprendizagem ao longo da vida; literacia e, por fim, autoestima. Neste tipo de estudo, privilegia-se o método qualitativo, bem como a entrevista e a observação como técnicas de recolha de dados adequadas ao mesmo. Por esta via, o que se pretende é analisar o perfil dos alunos que frequentam a Academia Sénior de Estremoz, bem como as competências de literacia que daí advêm e como capítulo final, verificar de que forma a autoestima é potenciada pelos intervenientes no projeto, por via das atividades desenvolvidas. Desta mesma forma, pretende-se analisar as perceções que os intervenientes no projeto detêm acerca da promoção das competências de literacia nos idosos, no referido contexto específico.
- Measurement of differential and integrated fiducial cross sections for Higgs boson production in the four-lepton decay channel in pp collisions at $ \sqrt{s}=7 $ and 8 TeVPublication . CMS collaboration (2302 authors); Hollar, Jonathan; Calpas, Betty; Nayak, Aruna; Bargassa, Pedrame; Beirão Da Cruz E Silva, Cristóvão; Di Francesco, Agostino; Faccioli, Pietro; Ferreira Parracho, Pedro Guilherme; Gallinaro, Michele; Leonardo, Nuno; Lloret Iglesias, Lara; Nguyen, Federico; Rodrigues Antunes, Joao; Seixas, Joao; Toldaiev, Oleksii; Vadruccio, Daniele; Varela, Joao; Vischia, Pietro; David Tinoco Mendes, Andre; Silva, Pedro; Musella, Pasquale; Pela, JoaoIntegrated fiducial cross sections for the production of four leptons via the H → 4ℓ decays (ℓ = e, μ) are measured in pp collisions at $ \sqrt{s}=7 $ and 8TeV. Measurements are performed with data corresponding to integrated luminosities of 5.1 fb$^{−1}$ at 7TeV, and 19.7 fb$^{−1}$ at 8 TeV, collected with the CMS experiment at the LHC. Differential cross sections are measured using the 8 TeV data, and are determined as functions of the transverse momentum and rapidity of the four-lepton system, accompanying jet multiplicity, transverse momentum of the leading jet, and difference in rapidity between the Higgs boson candidate and the leading jet. A measurement of the Z → 4ℓ cross section, and its ratio to the H → 4ℓ cross section is also performed. All cross sections are measured within a fiducial phase space defined by the requirements on lepton kinematics and event topology. The integrated H → 4ℓ fiducial cross section is measured to be 0. 56$_{− 0.44}^{+ 0.67}$ (stat)$_{− 0.06}^{+ 0.21}$ (syst) fb at 7 TeV, and 1. 11$_{− 0.35}^{+ 0.41}$ (stat)$_{− 0.10}^{+ 0.14}$ (syst) fb at 8 TeV. The measurements are found to be compatible with theoretical calculations based on the standard model.