Browsing by Author "Silva, N"
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- Effects of active video games on metabolic and cardiovascular systems in adults: systematic reviewPublication . Afonso, J; Almeida, M de; Raposo, M; Silva, N; Alves Lopes, AntónioIntroduction: In our society, the influence of technology is growing fast and its use occupies a large amount of time during the general population’s daily life, which may lead to a sedentary lifestyle. New technologies have been developed to promote physical activity, which can be named exergames or active video games. These platform games combine video games with physical activity. Objectives: Review systematically the scientific evidence about the effects of exergames in the metabolic and cardiovascular systems in the adult population, recommending future investigation. Methodology: Only RCT’s (Random Controlled Trials) were included in English and Portuguese, enclosing adults playing exergames and the results of evaluations of their metabolic and cardiovascular systems. The databases used were: Pubmed, Cochrane, PEDro, EBSCO, IEEXplor. The selection of the articles was made by four independent revisers, remaining only three articles of the initial 189. These three were methodologically evaluated using the PEDro scale. Results: All studies found evaluated the cardiac frequency, the O2 maximum consumption and the energy expenditure. Other evaluated items included perceived exertion, general physical condition, body mass index, arterial pressure (AP), walking distance and exercise adherence. All studies demonstrate significant differences in the results of the experimental group, on at least one of the variables at study. Conclusions: Examining the results, consensus is established, regarding the efficacy of video-games in energy consumption. However there isn’t sufficient evidence to reach conclusions about the other parameters. The studies did not show homogeneity, which makes it impossible to generalize the results to the population. More RCT’s are needed to reach significant conclusions, concerning the efficacy of active video-games in the metabolic and cardiovascular systems of adults, revealing the importance and necessity of future studies in this area.
- Etiology of bronchiolitis in a hospitalized pediatric population: prospective multicenter studyPublication . Antunes, H; Rodrigues, H; Silva, N; Ferreira, C; Carvalho, F; Ramalho, H; Gonçalves, A; Branca, FBACKGROUND: In 2006, bronchiolitis due to adenovirus nosocomial infections resulted in the closure of a pediatric department in northern Portugal. OBJECTIVES: To determine the etiology of bronchiolitis in northern Portugal. STUDY DESIGN: It was a prospective multicenter study on the etiology of bronchiolitis during the respiratory syncytial virus (RSV) season (November-April). Children < or = 24 months of age admitted for a first wheezing episode were included. Nasopharyngeal specimens were analyzed by an indirect immunofluorescent-antibody assay (IFA) for RSV, adenovirus (HAdV), parainfluenza (PIV) 1-3 and influenza (IV) A and B and by polymerase chain reaction (PCR) or reverse transcription-PCR for the same viruses and for human metapneumovirus (hMPV), bocavirus (HBoV), rhinovirus (HRV), coronaviruses (229/E; NL63; OC43; HKU1) and enterovirus. RESULTS: During this period, 253 children were included, 249 IFA analyses and 207 PCRs were performed. IFA detected RSV in 58.1%; PCR increased it to 66.7%. IFA detected HAdV in 3.2%, PCR 10.0%. PCR detected IV A in 5; IV B in 2; PIV 1 in 6, PIV 2 in 4 and PIV 3 in 11 cases. HBoV, as single agent in 2 cases, and HRV were positive in 8 samples and hMPV in 11. With this virus panel, 19.7% remained without etiology. CONCLUSIONS: The most frequent agent was RSV, followed by HAdV. PCR can be cost-effective and more accurate than IFA, which is crucial for HAdV that may be associated with significant mortality (IFA alone did not detect 2/3 of the cases).
- Immune disease expressed in liver and platelets in an adolescent: a case reportPublication . Antunes, H; Rocha, R; Silva, N; Pontes, T; Antunes, A; Martins, SWe report a case of a 15-year-old boy with autoimmune hepatitis lacking common serologic markers and normal gammaglobulinemia associated with immune thrombocytopenia and family history of psoriasis. He presented to our department with a 4-year history of a cervical posterior lymphadenopathy and recent petechiae. Previous laboratory results 6 months before already showed hepatocellular injury. After exclusion of other causes, the diagnosis of autoimmune hepatitis was made based on clinical grounds, associated immune disorder and histological features of liver biopsy.The authors alert for this atypical presentation of autoimmune hepatitis and associated immune thrombocytopenia.