Browsing by Author "Pinheiro, Maria F."
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- Application of indels (investigator DIPplex) in mixture samplesPublication . Carvalho, Ana; Cainé, Laura; Carvalho, Raquel; Pinheiro, Maria F.The main goal of this work was to study the application of the Investigator DIPplex kit to interpret mixtures linked with forensic cases, essentially those involved in the analysis of sexual crime samples. The study of these polymorphisms was performed in mixtures of two DNA controls included in commercial kits for the STRs typing, one male and the other female. The analysis was done according to the kit's manufacturer manual. The results were surprisingly better than expected, as the mixture interpretations were straightforward.
- Interest of X chromosome (Argus X-12 kit) in complex kinship analysisPublication . Cainé, Laura; Carvalho, Raquel; Costa, Sérgio; Pereira, Maria F.; Pinheiro, Maria F.X-chromosomal short tandem repeats (X-STRs) have proven to be informative and useful in complex relationship testing. Paternity trio cases can most easily be solved with only autosomal STRs markers, while test of paternity duos involving more complex family relations could gain from X-chromosomal testing. The main goal of the present study was to investigate twelve X-STR markers (DXS7132, DXS7423, DXS8378, DXS10074, DXS10079, DXS10101, DXS10103, DXS10134, DXS10135, DXS10146, DXS10148, and HPRTB) based on a Portuguese population sample, and their ability to solve complex kinship cases. Evaluations of statistical parameters of interest were also considered.
- Population data of 12 X-STR loci in a North of Portugal samplePublication . Cainé, Laura; Costa, Sérgio; Pinheiro, Maria F.