Browsing by Author "Gomes, J"
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- Bleomycin-induced flagellate hyperpigmentationPublication . Resende, C; Araújo, C; Gomes, J; Brito, CBleomycin is a chemotherapeutic agent used in the treatment of different tumours. It has several side effects, including flagellate hyperpigmentation, which is a unique and a well-documented side effect of bleomycin therapy. We report a case of a 23-year-old woman with a personal history of ovarian dysgerminoma, who developed flagellate hyperpigmentation on trunk after bleomycin therapy.
- Colloid milium successfully treated with MAL-PDTPublication . Gomes, J; Ventura, F; Duarte, ML; Brito, C
- Contact dermatitis due to Centella asiaticaPublication . Gomes, J; Pereira, T; Vilarinho, C; Duarte, ML; Brito, C
- Cutaneous Phaeohyphomycosis Caused by Alternaria alternata Unresponsive to Itraconazole TreatmentPublication . Gomes, J; Vilarinho, C; Duarte, ML; Brito, CCutaneous alternariosis is an opportunistic infection that has been described mainly in patients treated with corticosteroids. We report a case of dermal alternariosis occurring in a woman treated with corticosteroids after a neurosurgery that was unresponsive to itraconazole. Treatment with intravenous voriconazole was initiated, followed by oral protocol, with marked improvement of the lesions.
- Ecthyma gangrenosum secondary to severe invasive infection caused by Escherichia coli.Publication . Gomes, J; Vilarinho, C; Ventura, F; Vieira, AP; Brito, C
- Efficacy and safety of etanercept in patients with psoriasis and hepatitis CPublication . Ventura, F; Gomes, J; Duarte, ML; Fernandes, JC; Brito, C
- Galli-galli disease: a rare acantholytic variant of dowling-degos diseasePublication . Gomes, J; Labareda, J; Viana, IGalli-Galli disease is a rare acantholytic variant of Dowling-Degos disease, with few cases reported in the literature. We describe a case of Galli-Galli disease and review the literature.
- Giant pilomatricoma in a patient with tuberous sclerosis, both diagnosed in the adult life.Publication . Resende, CI; Gomes, J; Duarte, ML; Brito, CPilomatricoma is a relatively common benign skin neoplasm originating from the hair follicle matrix cells. β-Catenin is a subunit of the cadherin protein complex. It acts as an intracellular signal transducer that influences cell differentiation and proliferation. This protein was recently involved in the formation of hair follicle-related tumours, including pilomatricomas. Tuberous sclerosis (TS) is an inherited neurocutaneous disease, which is characterised by pleomorphic features involving many organs, hamartomas in multiple organ systems and by the fact that it is usually diagnosed early in life. We reported a case of a Caucasian patient with TS and a giant pilomatricoma, both diagnosed in the adult life.
- Intravenous thrombolysis is more effective in ischemic cardioembolic strokes than in non-cardioembolic?Publication . Rocha, S; Pires, A; Gomes, J; Sousa, F; Pinho, J; Rodrigues, M; Ferreira, C; Machado, A; Maré, R; Fontes, JRIt was suggested that intravenous thrombolysis (IT) leads to larger extent recanalization in cardioembolic stroke. In this work we assess if this has beneficial clinical traduction. METHOD: We evaluated 177 patients undergoing IT, which were categorized into cardioembolic (CE) and non-cardioembolic (NCE). National Institutes of Health Stroke Scale (NIHSS) and modified Rankin scale were compared. RESULTS: The mean age was 67.4±12.01 and 53.8% were male. The mean NIHSS was: 14 (admission), 9 (24 h) and 6 (discharge), similar in subgroups. The difference between NIHSS at admission and 24 hours was 4.17±4.92 (CE: 4.08±4.71; NCE: 4.27±5.17, p=0.900) and at admission and discharge there was an average difference of 6.74±5.58 (CE: 6.97±5.68; NCE: 6.49±5.49, p=0.622). The mRS at discharge and 3 months was not significantly different by subtype, although individuals whose event was NCE are more independent at 3 months. CONCLUSION: Ours findings argue against a specific paper of IT in CE. It can result from heterogeneity of NCE group
- Melanoma maligno associado a nevo melanocíticoPublication . Gomes, J; Parente, J; Ferreira, L; Viana, I; Vale, EObjectives: To determine clinical and histopathological differences between melanoma associated with nevus (MAN) and de novo melanoma (MN). Methods: Retrospective study of all cases of cutaneous melanoma diagnosed between 2001 and 2009 in Centro de Dermatologia Médico-Cirúrgica de Lisboa. Results: Of the 397 melanomas included, 52.6% were of feminine sex and 47.4% of the masculine. Of these melanomas only 9.3% were histologically associated with nevus, with discrete predominance of cases in the feminine sex (54%, p=0,033). In the group of the MAN the average of ages was slightly inferior (56,5 vs 59,3 years, p=0,577). The trunk was the preferential localization of all the melanomas (42.1%, p=0,005). Histologically the superficial spreading subtype was more frequently associated with MAN. The MAN were thinner than the MN (1,42 versus 2,13 mm, p=0,030), specially in the feminine sex (0,99mm, p=0,031). The Breslow tumor thickness and the presence of ulceration had a significant statistical correlation with the metastatic spread and the mortality by melanoma. Conclusions: The majority of the melanomas seem to arise de novo. In our study, factors that were significantly associated with MAN include feminine sex, trunk location, younger age, inferior Breslow thickness and superficial spreading subtype.