Browsing by Author "Flores, P"
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- E. Coli e Infecção Urinária novos Perfis de Susceptibilidade aos AntibióticosPublication . Mendes, AL; Flores, P; Menezes, MF; Neto, AS
- Experiência de um serviço de pediatria no apoio pós-operatório a correção da escoliosePublication . Paiva-Pereira, M; Flores, P; Castro-Faria, H; Neto, AS; Mineiro, JD
- Experiência de um serviço de pediatria no apoio pós-operatório a correção da escoliosePublication . Paiva-Pereira, M; Flores, P; Castro-Faria, H; Neto, AS; Draper Mineiro, J
- Neck and supraclavicular lymphadenopathy secondary to 9-valent human papillomavirus vaccinationPublication . Pereira, MP; Flores, P; Neto, ASWe present two clinical cases of lymphadenopathy after vaccination with the human papillomavirus (HPV) 9-valent vaccine: an asymptomatic 11-year-old boy with inferior cervical and supraclavicular lymphadenopathy, and a 13-year-old girl who presented with lymphadenopathy. In both cases, medical history was unremarkable and there was no recent infection, or other clinical findings. Both adolescents had received the HPV 9-valent vaccine in the previous week. In the first case, blood tests, ultrasonography and biopsy were performed, while in the second, a watchful waiting strategy was adopted. In both cases, the lymphadenopathy resolved spontaneously. The boy received the second dose of the vaccine 6 months later and lymphadenopathy reappeared. The Naranjo scale was applied, classifying the events as definite (in the case of the boy) and probable (girl) adverse drug reactions. The vaccine is safe, but recognising this minor adverse event is important to prevent unnecessary investigation and reduce patient and parental anxiety.
- Pancreatite Aguda - casuística de 10 anos do Serviço de Pediatria do Hospital Cuf DescobertasPublication . Mendes, AL; Flores, P; Neto, AS
- Pancreatite Aguda: Casuística de 10 anos do Centro da Criança do HCDPublication . Mendes, AL; Neto, AS; Flores, P
- A randomized trial of nebulized 3% hypertonic saline with salbutamol in the treatment of acute bronchiolitis in hospitalized infantsPublication . Flores, P; Mendes, AL; Neto, ASOBJECTIVE: Acute bronchiolitis is a common disorder of infants that often results in hospitalization. Apart from supportive care, no therapy has been shown to influence the course of the disease, except for a possible effect of nebulized hypertonic saline (HS). To determine whether this does have beneficial effects on length of stay in hospital or on severity scores, we undertook a double-blind, randomized, controlled trial in a pediatric department of a Portuguese hospital. METHODS: Previously healthy infants, younger than 12 months, hospitalized with mild-to-moderate acute viral bronchiolitis were randomized to receive either nebulized 3% (hypertonic, HS) or 0.9% (normal, NS) saline during their entire hospital stay. Primary endpoints were: length of hospital stay and severity scores on each day of hospitalization. Need for supplemental oxygen, further add-on medications and adverse effects were also analyzed. RESULTS: Sixty-eight patients completed the study (HS: 33; NS: 35). The median length of hospital stay did not differ between groups: HS: 5.6 ± 2.3 days; NS: 5.4 ± 2.1 days (P = 0.747). We found no difference between groups in severity scores from day 1 to day 4. There were no differences in need for supplemental oxygen or add-on medications. Patients in HS group had significantly more cough (46% vs. 20%, P = 0.025) and rhinorrhoe (58% vs. 31%, P = 0.30). CONCLUSION: This study does not support the use of nebulized HS over NS in therapy of hospitalized children with mild-to-moderate acute viral bronchiolitis