Percorrer por autor "Duarte, ML"
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- Association of adult mastocytosis with M541L in the transmembrane domain of KITPublication . Rocha, J; Duarte, ML; Marques, H; Torres, F; Tavares, P; Silva, A; Brito, C
- Colloid milium successfully treated with MAL-PDTPublication . Gomes, J; Ventura, F; Duarte, ML; Brito, C
- Contact dermatitis due to Centella asiaticaPublication . Gomes, J; Pereira, T; Vilarinho, C; Duarte, ML; Brito, C
- Cutaneous Phaeohyphomycosis Caused by Alternaria alternata Unresponsive to Itraconazole TreatmentPublication . Gomes, J; Vilarinho, C; Duarte, ML; Brito, CCutaneous alternariosis is an opportunistic infection that has been described mainly in patients treated with corticosteroids. We report a case of dermal alternariosis occurring in a woman treated with corticosteroids after a neurosurgery that was unresponsive to itraconazole. Treatment with intravenous voriconazole was initiated, followed by oral protocol, with marked improvement of the lesions.
- Efficacy and safety of etanercept in patients with psoriasis and hepatitis CPublication . Ventura, F; Gomes, J; Duarte, ML; Fernandes, JC; Brito, C
- Giant pilomatricoma in a patient with tuberous sclerosis, both diagnosed in the adult life.Publication . Resende, CI; Gomes, J; Duarte, ML; Brito, CPilomatricoma is a relatively common benign skin neoplasm originating from the hair follicle matrix cells. β-Catenin is a subunit of the cadherin protein complex. It acts as an intracellular signal transducer that influences cell differentiation and proliferation. This protein was recently involved in the formation of hair follicle-related tumours, including pilomatricomas. Tuberous sclerosis (TS) is an inherited neurocutaneous disease, which is characterised by pleomorphic features involving many organs, hamartomas in multiple organ systems and by the fact that it is usually diagnosed early in life. We reported a case of a Caucasian patient with TS and a giant pilomatricoma, both diagnosed in the adult life.
- Indeterminate cell histiocytosis in association with acute myeloid leukemiaPublication . Ventura, F; Pereira, T; Duarte, ML; Marques, H; Pardal, F; Brito, CIndeterminate cell histiocytosis (ICH) is a rare proliferative disorder, in which the predominant cells share morphologic and immunophenotypic features from both Langerhans and non-Langerhans cell histiocytosis. We describe a 62-year-old man presenting a 2-month history of firm nodular lesions on the upper lip. Histopathology, immunohistochemical, and ultrastructural analysis showed typical findings of ICH. The patient was treated with thalidomide and almost complete regression of the lesions was reached within 7 months. Nevertheless, one month after remission, he developed an acute myeloid leukemia of the subtype monocytic leukemia (M5). The patient's condition rapidly worsened and he died due to a respiratory failure four weeks later. We present this case because apart of being rare it joins the effectiveness of thalidomide and the association with an acute monocytic leukemia. A review of the literature is made.
- Methylaminolevulinate photodynamic therapy for granuloma annulare: A case reportPublication . Rocha, J; Brito, C; Ventura, F; Duarte, ML
- Rapidly lethal dermatomyositis associated with cutaneous lymphangitis carcinomatosaPublication . Resende, C; Araújo, C; Duarte, ML; Brito, CA 70-year-old woman with a recent diagnosis of dermatomyositis (DM) presented to the dermatology department for study of a probably paraneoplastic syndrome. On examination, we observed discrete, indurated, reddish, painful plaques and nodules on her abdomen and both thighs. A cutaneous biopsy from an abdominal nodule, performed as part of the paraneoplastic workup, was suggestive of cutaneous lymphangitis carcinomatosa, secondary to unknown malignancy. An extensive investigation to locate the site of the primary tumour revealed no specific findings. A course of palliative chemotherapy with cisplatin and 5-fluorouracil was then given, but the patient's condition deteriorated and 6 months after her initial observation the patient died. We describe this case because, to our knowledge, the association between DM and cutaneous lymphangitis carcinomatosa has not been described yet in the literature and to highlight that, DM can be a rapidly lethal disease.
- Scleromyxedema diagnosis following unexplained encephalopathyPublication . Rodrigues, M; Machado, A; Ventura, F; Duarte, ML; Ferreira, C