Browsing by Author "Cunha, Maura"
Now showing 1 - 3 of 3
Results Per Page
Sort Options
- Economic burden of Parkinson’s disease and research trends: a bibliometric analysisPublication . Cunha, Maura; Almeida, Helena; Guimarães, Isabel; Ferreira, LaraBackground Parkinson’s disease (PD) is a neurodegenerative disorder associated with a range of motor and non-motor symptom leading to progressive disability that signifcantly impacts on health related-quality of life (HRQoL) and imposes a substantial economic burden. The overall trend and impact of research production on the economic burden of PD have not yet been documented. In this study, the objective is to describe, map and analyse the evolution and trend of research on the economic burden in PD. Therefore, the initial research questions were: (1) what are the main research keywords on costs in the feld of Parkinson’s disease? and (2) how do an author’s studies on the economic burden and costs of Parkinson’s disease infuence scientifc production? Methods: The data used were retrieved from the Web of Science over the past 25 years, from 1997 to 2022. A bibliometric analysis was performed on the basis of the number of articles, citations, published journals, authors, countries scientifc production and keywords plus. Results: A total of 140 articles that met the criteria were collected and analysed, covering 736 authors, 41 journals and 34 countries. The most productive country was the United States of America (80.71%) and, among the journals, the Movement Disorders journal was the one with the largest growth (n=27). According to the thematic map, the terms “quality of life”, “impact” and “illness” were considered as having a high level of centrality, a moderate density and a high frequency. In addition, the terms “quality-of-life”, “impact” and illness were the most relevant words. Conclusions This study provides an overview of global research trends on the economic burden of PD.
- The reflux symptom score-12: cross-cultural adaptation and validation for european portuguese speakers with laryngopharyngeal refluxPublication . Guimarães, Isabel; Batista, Ana P.; Quintal, Aldora; Bom, Rita; Romeiro, Cláudia; Saraiva, Madalena; Cunha, Maura; Ferreira, Daniela B.; Correia, Paula; Almeida, Lina; Torrejano, GabrielaAbstract: Objectives. To translate and cross-culturally adapt the 12-item reflux symptom score (RSS-12) to European Portuguese (EP) and determine its clinimetric properties for symptomatic individuals with laryngopharyngeal reflux (LPR). Study design. Multinational cross-sectional cohort study. Methods. The English RSS-12 was cross-culturally adapted according to the recommendations of the international guidelines. The validation study included the completion of the RSS-12, reflux symptom index, and voice handicap index by symptomatic and asymptomatic subjects with LPR. The RSS-12 was completed a second time by symptomatic subjects. Nine clinimetric properties were analyzed according to the international guidelines for validation of patient-reported outcome measures. Results. The EP RSS-12 is equivalent to the English version (content, depth, and scoring). A total of 155 adults (84 with LPR symptoms) aged 21–78 years participated in the validation study. Statistical analyses revealed high internal consistency (Cronbach alpha > 0.90), high test-retest reliability (intraclass correlation coefficient > 0.70, P < 0.001), low measurement error (Standard measure error of 5.21 for RSS and 1.59 for quality of life), good content validity (omission data < 1% and item-total correlations > 0.652), good construct validity (61.9% of the total item variance with moderate item loadings), strong concurrent validity with reflux symptom index (rp = 0.772, P < 0.001) and moderate validity with voice handicap index (rp = 0.531, P < 0. 001), and signi5cantly known-groups validity (P < 0.001). The EP RSS-12 showed cross-cultural validity with French and Persian versions and high predictive validity with a cut-off value > 8 for a sensitivity of 91.7% and a specificity of 91.5%. Conclusions. The EP RSS-12 retained the features of the English version and is a reliable and valid patient-reported outcome measure for EP individuals with LPR in the study.
- A voz na formação dos futuros terapeutas da falaPublication . Cunha, Maura; Guimarães, Isabel