Percorrer por autor "Abreu, Ana"
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- El papel de las Ciencias Forenses en la identificación de restos óseos - informe de un caso (poster)Publication . Costa Lopes, Miguel; Abreu, Ana; Amorim, António; Ribeiro, Teresa; Cunha, Eugénia; Eiras, Luísa
- Olanzapine: challenges in toxicological results interpretationPublication . Costa Lopes, Miguel; Abreu, Ana; Nascimento, João; Sardinha, Mário; Castañera, Antonio; Fonseca, Suzana; Franco, João; Nikolić, DobrilaFatal intoxications are a topic of great relevance in today's society and a massive challenge for pathologists all over the world. In post-mortem investigations it is often challenging to determine if and which drug(s) caused the death due to the post-mortem processes in a body. This study evaluates forensic fatal cases with positive blood levels for the antipsychotic Olanzapine. The aim of this study is to characterize the sample of such forensic autopsy cases and try to correlate the Olanzapine concentrations with the manner of death and cause of death attributed in the reports. We performed a retrospective, observational and descriptive study, analyzing the reports of forensic autopsies performed in the South Branch of the National Institute of Legal Medicine and Forensic Sciences, in Lisbon, Portugal, from 2013 until 2015. A total of 53 forensic autopsy cases characterized by the presence of Olanzapine were analyzed. Blood Olanzapine concentrations ranged from 10ng/ml to 4363ng/ml. The following variables were collected: sex, age, place of death, number of days between death and autopsy, clinical history, signals of putrefaction, cause of death, manner of death and ancillary tests performed, such as toxicological and histological exams. This study raises the need of awareness for the most common limitations that forensic pathologists face in the interpretation of toxicological results and indicate the need to create a reference table for each substance with our casuistic.
- Prevenção em Destaque - Portugal: Relatório inserido na iniciativa Prevention in your Country promovido pela EACPRPublication . Rocha, Evangelista; Ferreira, Rui Cruz; Abreu, Ana; Portugal, Rui; Nogueira, Paulo; Timóteo, Ana
- Reliability and validity of the global physical activity questionnaire for Portuguese adultsPublication . Ribeiro, Mariana; Fernandes, Elisabete; Borges, Mariana; Pires, Madalena; Melo, Xavier; Pinto, Fausto J.; Abreu, Ana; Pinto, RitaThe Global Physical Activity Questionnaire (GPAQ) has been used often to assess physical activity (PA) patterns. However, the European Portuguese version of this instrument has not been validated. We aimed to validate the self-administered GPAQ, version 2, (GPAQv2) for Portuguese adults. We included 32 participants in a pilot study of a Portuguese adaptation of the test and 108 participants in an assessment of their PA patterns and sedentary behavior (SB) through the GPAQv2. For its validation, we compared the GPAQv2 to the International PA Questionnaire-Long Form (IPAQ-LF) (concurrent validity) and the ActiGraph wGT3X-BT accelerometer (criterion validity). We evaluated PA and SB at baseline and after seven consecutive days. Test-retest reliability with the Kappa test (k) and the Intraclass Correlation Coefficient (ICC) ranged from strong to almost perfect (k: 0.864–0.976) and from moderate to excellent (ICC: 0.56–0.994), respectively. Concurrent validity, assessed by Spearman’s Correlation Coefficient, was moderate to substantial (rho: 0.471–0.680), and there was fair to substantial criterion validity (rho: 0.226–0.672). Bland-Altman plots showed that the GPAQv2 overestimated vigorous and moderate to vigorous PA and underestimated moderate PA. The largest difference values were related to SB, since the GPAQv2 underestimated sitting time. In sum, we found the GPAQv2 to have acceptable validity and reliability for assessing PA and SB patterns, and we recommend its use for Portuguese adults.