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Rubella in Sub-Saharan Africa and sensorineural hearing loss: a case control study

dc.contributor.authorCaroça, C
dc.contributor.authorVicente, V
dc.contributor.authorCampelo, P
dc.contributor.authorChasqueira, M
dc.contributor.authorCaria, H
dc.contributor.authorSilva, S
dc.contributor.authorPaixão, P
dc.contributor.authorPaço, J
dc.date.accessioned2017-02-05T17:17:39Z
dc.date.available2017-02-05T17:17:39Z
dc.date.issued2017-02-01
dc.description.abstractRubella infection can affect several organs and cause birth defects that are responsible for congenital rubella syndrome (CRS). Congenital hearing loss is the most common symptom of this syndrome, occurring in approximately 60% of CRS cases. Worldwide, over 100 000 babies are born with CRS every year. There is no specific treatment for rubella, but the disease is preventable by vaccination. Since 1969, the rubella vaccine has been implemented in many countries, but in Africa, only a few countries routinely immunize against rubella. The aim of this study was to estimate the rate of infection from the wild-type rubella virus in São Tomé and Príncipe by determining rubella seroprevalence with a DBS method. The goal of this study was to reinforce the need for implementation of the rubella vaccine in this country. As secondary objectives, the validation of a DBS method was first attempted and an association between seroprevalence and hearing loss was assessed.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBMC Public Health (2017) 17:146pt_PT
dc.identifier.doi10.1186/s12889-017-4077-2pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/17857
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectSíndrome de Rubéola Congénitapt_PT
dc.subjectSurdezpt_PT
dc.subjectÁfrica ao Sul do Saarapt_PT
dc.subjectPerda Auditiva Neurossensorialpt_PT
dc.subjectDeafnesspt_PT
dc.subjectRubella Syndrome, Congenitalpt_PT
dc.subjectHearing Loss, Sensorineuralpt_PT
dc.subjectAfrica South of the Saharapt_PT
dc.titleRubella in Sub-Saharan Africa and sensorineural hearing loss: a case control studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue1pt_PT
oaire.citation.startPage146pt_PT
oaire.citation.volume17pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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