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Randomized pilot study on the effects of sarcocornia as a salt substitute in arterial blood pressure and vascular function in healthy young adults

dc.contributor.authorPereira, Telmo
dc.contributor.authorCaldeira, Andreia Torres
dc.contributor.authorCaseiro, Armando
dc.contributor.authorOsório, Nádia
dc.contributor.authorMOREIRA DA SILVA, AIDA
dc.contributor.authorBarroca, MJ
dc.date.accessioned2022-09-29T11:44:39Z
dc.date.available2022-09-29T11:44:39Z
dc.date.issued2022-09-17
dc.description.abstractPrevious studies have shown that excessive salt intake is strongly associated with high blood pressure (HT), vascular dysfunction, and the overall risk of cardiovascular diseases. The aim of this study was to evaluate Sarcocornia effectiveness as a salt substitute, addressing its effect on cardiovascular function in healthy young individuals. Thirty healthy participants, aged 18 to 26 years, were randomized into two groups: the control group (CG) and the intervention group (IG). The IG used Sarcocornia powder as a salt substitute for cooking, and the CG used regular salt, during a period of 1 month. A baseline evaluation was performed before the participants started the intervention phase, and was repeated after a 30-day intervention period. Each evaluation included blood pressure (BP) measurement, carotid-femoral pulse wave velocity (PWV), and carotid pulse wave analysis (PWA), and blood samples were also collected for analysis. Sodium excretion was measured at baseline and after intervention through spot urine collection and analysis, a method suitable for this population but with known limitations. Baseline parameters were similar between groups and were within the normal range. Sodium excretion remained unchanged in the two evaluations in the CG, but significantly decreased after intervention in the IG. The reduction in sodium excretion in the IG was followed by a significant reduction in brachial and aortic systolic (SBP) and diastolic blood pressure (DBP), and also in PWV. No significant changes were observed in the CG in terms of cardiovascular parameters. This preliminary study conveys positive results in favor of Sarcocornia as a dietary substitute for regular salt, providing added evidence of the negative cardiovascular effects of high salt intake in young and healthy adults.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPereira, T.; Caldeira, A.T.; Caseiro, A.; Osório, N.; da Silva, A.M.; Barroca, M.J. Randomized Pilot Study on the Effects of Sarcocornia as a Salt Substitute in Arterial Blood Pressure and Vascular Function in Healthy Young Adults. Foods 2022, 11, 2888pt_PT
dc.identifier.doi10.3390/foods11182888pt_PT
dc.identifier.issn2304-8158
dc.identifier.urihttp://hdl.handle.net/10400.26/41863
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relation.publisherversionhttps://www.mdpi.com/2304-8158/11/18/2888/pdf?version=1663408551pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/pt_PT
dc.subjectHypertensionpt_PT
dc.subjectArterial stiffnesspt_PT
dc.subjectSaltpt_PT
dc.subjectSarcocorniapt_PT
dc.subjectHalophyte plantspt_PT
dc.subjectHipertensãopt_PT
dc.subjectRigidez vascularpt_PT
dc.subjectSaispt_PT
dc.subjectPlantas tolerantes a salpt_PT
dc.titleRandomized pilot study on the effects of sarcocornia as a salt substitute in arterial blood pressure and vascular function in healthy young adultspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceBasileia, Suíçapt_PT
oaire.citation.endPage12pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleFoodspt_PT
oaire.citation.volume11pt_PT
person.familyNamePereira
person.familyNameCaseiro
person.familyNameOsório
person.familyNameGONÇALVES MOREIRA DA SILVA
person.familyNameBarroca
person.givenNameTelmo
person.givenNameArmando
person.givenNameNádia
person.givenNameAIDA MARIA
person.givenNameMaria João Mendes Cardoso
person.identifier779139
person.identifierhttps://scholar.google.com.br/citations?user=rv5gBDIAAAAJ&hl=pt-PT
person.identifier.ciencia-idEB19-9F1B-9811
person.identifier.ciencia-id4012-A0D8-66D6
person.identifier.ciencia-id271E-2D9B-E7F3
person.identifier.ciencia-idB413-D306-A98E
person.identifier.ciencia-idE21B-CD54-E879
person.identifier.orcid0000-0001-9119-7774
person.identifier.orcid0000-0001-7844-0506
person.identifier.orcid0000-0001-9559-2165
person.identifier.orcid0000-0001-5258-7980
person.identifier.orcid0000-0002-9186-0975
person.identifier.ridM-4626-2013
person.identifier.ridL-8385-2013
person.identifier.scopus-author-id24391294200
person.identifier.scopus-author-id35738464000
person.identifier.scopus-author-id57188973499
person.identifier.scopus-author-idhttps://www.scopus.com/authid/detail.uri?authorId=6602767047
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication85969647-47cc-47ee-bec2-1360f30ae958
relation.isAuthorOfPublication3736a1f3-88d6-42fb-94fc-ecd5484412de
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relation.isAuthorOfPublication76a56654-b1a1-41f7-8bcf-ce1b95dc4809
relation.isAuthorOfPublication.latestForDiscovery76a56654-b1a1-41f7-8bcf-ce1b95dc4809

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