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Metabolic Profile and Cardiovascular Risk in a Population of Renal transplant recipients

2015Journal article Open access
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dc.contributor.authorGonçalves, M
dc.contributor.authorVieira, P
dc.contributor.authorResende, L
dc.contributor.authorDurães, J
dc.contributor.authorRosa, N
dc.contributor.authorTeixeira, JA
dc.contributor.authorSilva, G
dc.date.accessioned2019-12-05T16:15:42Z
dc.date.available2019-12-05T16:15:42Z
dc.date.issued2015
dc.description.abstractIntroduction. Cardiovascular disease is more common in renal transplant recipients (RTRs) than in the general population, and is the major cause of both graft loss and patient death in RTRs. Objectives. This study aimed to characterize the cardiovascular risk factors, calculate the 7-year risk for major adverse cardiac events and the 7-year risk for death in a population of RTRs using a cardiovascular risk calculator, and determine the main cardiovascular risk factors associated with increased prediction of major adverse cardiac event (MACE) and death. Patients. This is a retrospective review of clinical data from 121 RTRs who are in follow-up programs at our institution, and who had a functioning and stable graft for longer than 6 months. Results. Among 121 adult patients followed at our institution (59.5% males, mean age of 49.6 13.8 years, mean times for functioning grafts were 105 73.5 mo), 86.8% had hypertension, 19.8% had diabetes, 24.8% were current or former smokers, 61.9% had increased body mass index, and 71% had dyslipidemia. The 7-year risk for MACE was more than 10% in 38 (31.4%) patients with age, diabetes, and smoke being independent risk predictors. The 7-year risk for death was more than 10% in 56 (46.3%) patients with age, diabetes, blood pressure, smoking, and male gender being independent risk predictors. Conclusion. There is a high prevalence of cardiovascular risk factors in a population of RTRs, and there is increased risk for MACE and death. Accurate risk prediction is important for physician decision support and patient education, promoting improved cardiovascular health of RTRs, and thus prolonging the survival of both patients and graft.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationTransplantation Proceedings, 47, 985e988 (2015)pt_PT
dc.identifier.doidoi.org/10.1016/j.transproceed.2015.03.031pt_PT
dc.identifier.issn0041-1345/15
dc.identifier.urihttp://hdl.handle.net/10400.26/30395
dc.language.isoengpt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttp://dx.doi.org/10.1016/j.transproceed.2015.03.031pt_PT
dc.subjectRenal transplant recipientspt_PT
dc.subjectRTRs.pt_PT
dc.subjectmortalidade cardiovascularpt_PT
dc.subjectinsufuciencia renalpt_PT
dc.subjectMadeira Islandpt_PT
dc.subjectPortugalpt_PT
dc.subjectsurvivingpt_PT
dc.subjectsobrevidapt_PT
dc.titleMetabolic Profile and Cardiovascular Risk in a Population of Renal transplant recipientspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage988pt_PT
oaire.citation.startPage985pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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