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Uterine sarcomas: clinical presentation and MRI features

dc.contributor.authorSantos, Pedro
dc.contributor.authorCunha, Teresa Margarida
dc.date.accessioned2016-10-04T13:35:24Z
dc.date.available2016-10-04T13:35:24Z
dc.date.issued2015
dc.date.updated2016-07-23T11:55:45Z
dc.description.abstractUterine sarcomas are a rare heterogeneous group of tumors of mesenchymal origin, accounting for approximately 8% of uterine malignancies. They comprise leiomyosarcoma, endometrial stromal sarcoma, undifferentiated endometrial sarcoma, and adenosarcoma. Compared with the more common endometrial carcinomas, uterine sarcomas behave more aggressively and are associated with a poorer prognosis. Due to their distinct clinical and biological behavior, the International Federation of Gynecology and Obstetrics introduced a new staging system for uterine sarcomas in 2009, categorizing uterine carcinosarcoma as a variant of endometrial carcinoma, rather than a pure sarcoma. Magnetic resonance imaging (MRI) has a developing role in the assessment of these malignancies. Features such as tumor localization, irregular or nodular margins, necrosis, rapid growth, intense contrast enhancement, and restriction at diffusion-weighted imaging can suggest the diagnosis and help differentiate from more common leiomyomas and endometrial carcinoma. MRI is therefore extremely useful in preoperative detection and staging and, consequently, in determination of appropriate management. This pictorial review aims to discuss the clinical features of uterine sarcomas, as well as their most common appearances and distinct characteristics in MRI.pt_PT
dc.identifier1305-3825en_US
dc.identifier.citationPedro Santos; Teresa Margarida Cunha. Uterine Sarcomas: Clinical Presentation and MRI Features, Diagnostic and Interventional Radiology, 21, 1, 4-9, 2015.pt_PT
dc.identifier.doi10.5152/dir.2014.14053pt_PT
dc.identifier.issn1305-3825
dc.identifier.urihttp://hdl.handle.net/10400.26/14943
dc.language.isoengpt_PT
dc.titleUterine sarcomas: clinical presentation and MRI featurespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage9pt_PT
oaire.citation.startPage4pt_PT
oaire.citation.titleDiagnostic and interventional radiology (Ankara, Turkey)pt_PT
oaire.citation.volume21pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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