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Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis: Useless or useful? – A literature review

dc.contributor.authorAlpuim Costa, D
dc.contributor.authorAmaro, CE
dc.contributor.authorNunes, A
dc.contributor.authorCardoso, JS
dc.contributor.authorDaniel, PM
dc.contributor.authorRosa, I
dc.contributor.authorBranco, JV
dc.date.accessioned2022-08-07T21:47:28Z
dc.date.available2022-08-07T21:47:28Z
dc.date.issued2021
dc.description.abstractRadiotherapy (RT) is the backbone of multimodality treatment of more than half of cancer cases. Despite new modern RT techniques, late complications may occur such as radiation proctitis (RP). The natural history of RP is unpredictable. Minor symptoms may resolve spontaneously or require conservative treatment. On the other hand, for similar and uncomplicated clinical contexts, symptoms may persist and can even be refractory to the progressive increase in treatment measures. Over the last decades, an enormous therapeutic armamentarium has been considered in RP, including hyperbaric oxygen therapy (HBOT). Currently, the evidence regarding the impact of HBOT on RP and its benefits is conflicting. Additional prospective and randomised studies are necessary to validate HBOT's effectiveness in the 'real world' clinical practice. This article reviewed the relevant literature on pathophysiology, clinical presentation, different classifications and discuss RP management including a proposal for a therapeutic algorithm with a focus on HBOT.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationWorld J Gastroenterol . 2021 Jul 21;27(27):4413-4428.pt_PT
dc.identifier.doi10.3748/wjg.v27.i27.4413pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/41556
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectOxigenoterapia Hiperbáricapt_PT
dc.subjectProctitept_PT
dc.subjectLesões por Radiaçãopt_PT
dc.subjectHyperbaric Oxygenationpt_PT
dc.subjectProctitispt_PT
dc.subjectRadiation Injuriespt_PT
dc.titleHyperbaric oxygen therapy as a complementary treatment for radiation proctitis: Useless or useful? – A literature reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage4428pt_PT
oaire.citation.issue27pt_PT
oaire.citation.startPage4413pt_PT
oaire.citation.titleWorld Journal of Gastroenterologypt_PT
oaire.citation.volume27pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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