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A review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimens

dc.contributor.authorSoares, Sofia
dc.contributor.authorBarroso, Mário
dc.contributor.authorGallardo, Eugenia
dc.date.accessioned2022-07-26T16:00:50Z
dc.date.available2022-07-26T16:00:50Z
dc.date.issued2021
dc.description.abstractAntidepressants are a class of compounds widely used in clinical settings for the treatment of several diseases. In the last years there has been a considerable increase in their consumption, representing an important public health issue in several countries. Because they are substances with narrow therapeutic windows, and since they are capable of interacting with other classes of compounds, monitoring of these compounds is of relevance, minimizing the risk of medical interactions as well as side and toxic effects. In addition, understanding the extent of their use, their detection through routine toxicology tests and development of new methods for detection and monitoring is of extreme importance concerning public health, patient well-being, and implications in clinical and forensic situations. The main objective of this work is to perform a critical review on the biological samples used in the detection and quantification of antidepressants with special focus on the techniques for sample preparation.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSoares, S., Barroso, M., & Gallardo, E. (2021). A review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimens. Reviews in Analytical Chemistry, 40(1), 12–32pt_PT
dc.identifier.doi10.1515/revac-2021-0124pt_PT
dc.identifier.issn2191-0189
dc.identifier.urihttp://hdl.handle.net/10400.26/41467
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherDe Gruyterpt_PT
dc.relationHealth Sciences Research Centre
dc.relation.publisherversionhttps://www.degruyter.com/document/doi/10.1515/revac-2021-0124/htmlpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAntidepressantspt_PT
dc.subjectBiological specimenspt_PT
dc.subjectSample pretreatment techniquespt_PT
dc.subjectAnalytical instrumentationpt_PT
dc.titleA review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimenspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleHealth Sciences Research Centre
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00709%2F2020/PT
oaire.citation.conferencePlaceBERLIN, Germanypt_PT
oaire.citation.endPage32pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage12pt_PT
oaire.citation.titleReviews in Analytical Chemistrypt_PT
oaire.citation.volume40pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameBarroso
person.givenNameMário
person.identifier.ciencia-id5110-F476-ECCC
person.identifier.orcid0000-0001-8848-2734
person.identifier.scopus-author-id35329243100
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication294b555e-48c4-4013-b981-b8917400c56c
relation.isAuthorOfPublication.latestForDiscovery294b555e-48c4-4013-b981-b8917400c56c
relation.isProjectOfPublication4ca3c3c9-1802-4c7f-8730-9547236896fe
relation.isProjectOfPublication.latestForDiscovery4ca3c3c9-1802-4c7f-8730-9547236896fe

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