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First-episode psychosis in a 15 year-old female with clinical presentation of anti-NMDA receptor encephalitis: a case report and review of the literature

dc.contributor.authorMoura, M
dc.contributor.authorSilva-dos-Santos, Amílcar
dc.contributor.authorAfonso, J
dc.contributor.authorTalina, M
dc.date.accessioned2016-08-09T21:21:10Z
dc.date.available2016-08-09T21:21:10Z
dc.date.issued2016
dc.description.abstractBACKGROUND: Anti-NMDA receptor encephalitis is an autoimmune disease that was identified in 2007, and manifests in a stepwise manner with psychiatric, neurological and autonomic symptoms. The disease is caused by autoantibodies against NMDA receptors. It can have a paraneoplastic origin, mainly secondary to ovarian teratomas, but it can also be unrelated to the tumor. This disease can affect both sexes and all ages. CASE PRESENTATION: Here, we present a case of a 15 year-old female adolescent with first-episode psychosis with anti-NMDA receptor encephalitis not related to tumor, which manifested with delusion, hallucinations, panic attacks, agitation, and neurological symptoms, and later with autonomic instability. She was treated with immunotherapy and psychiatric medication resulting in improvement of her main psychiatric and neurological symptoms. CONCLUSION: Our main objective in presenting this case is to alert clinicians to this challenging and recent disease that has a clinical presentation that might resemble a functional psychiatric condition and can be underdiagnosed in the context of child and adolescent psychiatrypt_PT
dc.identifier.citationBMC Res Notes. 2016 Jul 29;9(1):374.pt_PT
dc.identifier.doi10.1186/s13104-016-2180-6pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/14435
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectTranstornos Psicóticospt_PT
dc.subjectAdolescentept_PT
dc.subjectEncefalite Antirreceptor de N-Metil-D-Aspartatopt_PT
dc.titleFirst-episode psychosis in a 15 year-old female with clinical presentation of anti-NMDA receptor encephalitis: a case report and review of the literaturept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue1pt_PT
oaire.citation.startPage374pt_PT
oaire.citation.volume9pt_PT
person.familyNameSilva-dos-Santos
person.givenNameAmílcar
person.identifier279697
person.identifier.ciencia-id031C-29D7-85D8
person.identifier.orcid0000-0001-9537-4782
person.identifier.ridI-5904-2014
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationd75b4a9c-e3fb-4b6d-8fc5-3e39d77adf9a
relation.isAuthorOfPublication.latestForDiscoveryd75b4a9c-e3fb-4b6d-8fc5-3e39d77adf9a

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