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Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review

dc.contributor.authorAlves, Rubina
dc.contributor.authorGrimalt, R
dc.date.accessioned2022-11-21T17:47:17Z
dc.date.available2022-11-21T17:47:17Z
dc.date.issued2020
dc.descriptionKey Summary Points Platelet-rich plasma (PRP) is an autologous blood product containing high concentrations of platelets in a small volume of plasma. PRP may act at the dermal papilla cells to promote new hair growth, contribute to faster telogen–anagen transition, and increase hair density; good results should be expected with the use of PRP. In androgenetic alopecia, a positive effect was demonstrated after injections of PRP (mainly after three treatments), showing an increase of hair density in most patients. The results obtained with the use of PRP in alopecia areata are not so consistent. PRP might work in some types of cicatricial alopecia, such as lichen planopillaris, central centrifugal cicatricial alopecia, and frontal fibrosing alopecia.pt_PT
dc.description.abstractThe concept and description of platelet-rich plasma (PRP) started in the field of hematology and is being extensively used in other fields of medicine. Interest in the application of PRP has been increasing in dermatology, such as in tissue regeneration, wound healing, scar revision, skin-rejuvenating effects, and alopecia. PRP is an autologous blood product containing high concentrations of platelets in a small volume of plasma. Different preparations of PRP may lead to different volumes of PRP, platelet concentration, and presence or absence of leukocytes. PRP is being used as a new therapy for some types of non-cicatricial alopecia such as androgenetic alopecia (AGA) and alopecia areata (AA) and, recently, new insights refer to the possibility of action in the field of cicatricial alopecia, like lichen planopillaris (LPP) and frontal fibrosing alopecia (FFA). This article aims to identify the major indications for the application of PRP in the field of hair disorders, including non-cicatricial and cicatricial alopecia.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1007/s13555-020-00408-5pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/42354
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherDermatol Ther (Heidelb)pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectAlopeciapt_PT
dc.subjectAlopecia areatapt_PT
dc.subjectAndrogenetic alopeciapt_PT
dc.subjectCentral centrifugal cicatricialalopeciapt_PT
dc.subjectCicatricial alopeciapt_PT
dc.subjectFrontal fibrosing alopeciapt_PT
dc.subjectNon-cicatricialalopeciapt_PT
dc.subjectLichen planopillarispt_PT
dc.subjectPlatelet-rich plasmapt_PT
dc.titlePlatelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage633pt_PT
oaire.citation.issue4pt_PT
oaire.citation.startPage623pt_PT
oaire.citation.titleDermatology and Therapypt_PT
oaire.citation.volume10pt_PT
person.familyNameAlves
person.familyNamegrimalt
person.givenNameRubina
person.givenNameramon
person.identifier.orcid0000-0002-9542-8020
person.identifier.orcid0000-0001-7204-8626
person.identifier.scopus-author-id30867491800
person.identifier.scopus-author-id7003773371
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication031d2ac5-7a3e-468f-8481-d06f68092e0d
relation.isAuthorOfPublicationb4b0d944-7825-412b-8223-4af29429d33f
relation.isAuthorOfPublication.latestForDiscoveryb4b0d944-7825-412b-8223-4af29429d33f

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