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Endometrial cancer

dc.contributor.authorHorta, Mariana
dc.contributor.authorCunha, Teresa Margarida
dc.date.accessioned2017-01-25T16:05:54Z
dc.date.available2017-01-25T16:05:54Z
dc.date.issued2016
dc.date.updated2017-01-21T16:03:43Z
dc.description.abstractEndometrial cancer is the most common gynecological malignancy in well-developed countries. Biologically and clinicopathologically, endometrial carcinomas are divided into two types: type 1 or estrogen-dependent carcinomas and type 2 or estrogen-independent carcinomas. Type 1 cancers correspond mainly to endometrioid carcinomas and account for approximately 90 % of endometrial cancers, whereas type 2 cancers correspond to the majority of the other histopathological subtypes. The vast majority of endometrial cancers present as abnormal vaginal bleedings in postmenopausal women. Therefore, 75 % of cancers are diagnosed at an early stage, which makes the overall prognosis favorable. The first diagnostic step to evaluate women with an abnormal vaginal bleeding is the measurement of the endometrial thickness with transvaginal ultrasound. If endometrial thickening or heterogeneity is confirmed, a biopsy should be performed to establish a definite histopathological diagnosis. Magnetic resonance imaging is not considered in the International Federation of Gynaecology and Obstetrics staging system. Nonetheless it plays a relevant role in the preoperative staging of endometrial carcinoma, helping to define the best therapeutic management. Moreover, it is important in the diagnosis of treatment complications, in the surveillance of therapy response, and in the assessment of recurrent disease.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier0942-5373en_US
dc.identifier.citationMariana Horta; Teresa Margarida Cunha. Endometrial Cancer, In tmargarida@gmail.com, 1-30, ISBN: 0942-5373. Berlin: Springer Berlin Heidelberg, 2016.pt_PT
dc.identifier.doi10.1007/174_2016_84pt_PT
dc.identifier.issn0942-5373
dc.identifier.urihttp://hdl.handle.net/10400.26/17722
dc.language.isoengpt_PT
dc.publisherSpringer Berlin Heidelbergpt_PT
dc.titleEndometrial cancerpt_PT
dc.typebook part
dspace.entity.typePublication
oaire.citation.titleMedical radiologypt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typebookPartpt_PT

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