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LOCUS (LOng Covid–Understanding Symptoms, events and use of services in Portugal): A three-component study protocol

2023Journal article Open access
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dc.contributor.authorDinis Teixeira, JP
dc.contributor.authorSantos, MJ
dc.contributor.authorSoares, P
dc.contributor.authorAzevedo, L
dc.contributor.authorBarbosa, P
dc.contributor.authorVilas-Boas, A
dc.contributor.authorCordeiro, JV
dc.contributor.authorDias, S
dc.contributor.authorFonseca, M
dc.contributor.authorGoes, AR
dc.contributor.authorLobão, MJ
dc.contributor.authorMoniz, M
dc.contributor.authorNóbrega, S
dc.contributor.authorPeralta-Santos, A
dc.contributor.authorRamos, V
dc.contributor.authorRocha, JV
dc.contributor.authorda Silva, AC
dc.contributor.authorBrazão, ML
dc.contributor.authorLeite, A
dc.contributor.authorNunes, C
dc.date.accessioned2023-10-08T20:29:55Z
dc.date.available2023-10-08T20:29:55Z
dc.date.issued2023
dc.description.abstractApproximately 10% of patients experience symptoms of Post COVID-19 Condition (PCC) after a SARS-CoV-2 infection. Akin acute COVID-19, PCC may impact a multitude of organs and systems, such as the cardiovascular, respiratory, musculoskeletal, and neurological systems. The frequency and associated risk factors of PCC are still unclear among both community and hospital settings in individuals with a history of COVID-19. The LOCUS study was designed to clarify the PCC's burden and associated risk factors. LOCUS is a multi-component study that encompasses three complementary building blocks. The "Cardiovascular and respiratory events following COVID-19" component is set to estimate the incidence of cardiovascular and respiratory events after COVID-19 in eight Portuguese hospitals via electronic health records consultation. The "Physical and mental symptoms following COVID-19" component aims to address the community prevalence of self-reported PCC symptoms through a questionnaire-based approach. Finally, the "Treating and living with Post COVID-19 Condition" component will employ semi-structured interviews and focus groups to characterise reported experiences of using or working in healthcare and community services for the treatment of PCC symptoms. This multi-component study represents an innovative approach to exploring the health consequences of PCC. Its results are expected to provide a key contribution to the optimisation of healthcare services design.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPLoS One . 2023 Apr 26;18(4):e0285051.pt_PT
dc.identifier.doi10.1371/journal.pone.0285051pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/47119
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectCOVID-19pt_PT
dc.subjectSARS-CoV-2pt_PT
dc.subjectSíndrome Pós-COVID-19 Agudapt_PT
dc.subjectPost-Acute COVID-19 Syndromept_PT
dc.titleLOCUS (LOng Covid–Understanding Symptoms, events and use of services in Portugal): A three-component study protocolpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue4pt_PT
oaire.citation.startPagee0285051pt_PT
oaire.citation.titlePLOS ONEpt_PT
oaire.citation.volume18pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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