Publication
Searching relevant polymorphisms of CYP2B6 in HIV infected patients
| dc.contributor.author | Tomaz, R. | |
| dc.contributor.author | Fernandes, A. | |
| dc.contributor.author | Cruz, J. P. | |
| dc.contributor.author | Martins, R. | |
| dc.contributor.author | Morais, J. G. | |
| dc.contributor.author | Ribeiro, A. C. | |
| dc.date.accessioned | 2016-09-20T10:31:16Z | |
| dc.date.available | 2016-09-20T10:31:16Z | |
| dc.date.issued | 2015-11-27 | |
| dc.description | Poster presented at the From Basic Sciences to Clinical Research - First International Congress of CiiEM. Egas Moniz, Caparica, Portugal, 27- 28 November 2015 | pt_PT |
| dc.description.abstract | "The CYP2B6 belongs to the family of Cytochrome P450 enzymes that catalyze the metabolism of a wide variety of drugs, including the anti-retroviral EFV. The CYP2B6 gene, that has been mapped in the chromosome 19, is highly polymorphic and some SNP, namely 516G>T and 785A>G, are associated with decreased protein expression. These variants are related to phenotypes that are characterized as EFV poor metabolizers, and consequently to episodes of neurotoxicity." | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.26/14760 | |
| dc.language.iso | eng | pt_PT |
| dc.subject | Polymorphisms | pt_PT |
| dc.subject | CYP2B6 | pt_PT |
| dc.subject | HIV | pt_PT |
| dc.title | Searching relevant polymorphisms of CYP2B6 in HIV infected patients | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FDTP-FTO%2F1747%2F2012/PT | |
| oaire.citation.conferencePlace | Egas Moniz, Caparica, Portugal | pt_PT |
| oaire.citation.title | From Basic Sciences to Clinical Research - First International Congress of CiiEM | pt_PT |
| oaire.fundingStream | 3599-PPCDT | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
| relation.isProjectOfPublication | e22bc3ef-20a4-4173-a3c1-66d4f295e954 | |
| relation.isProjectOfPublication.latestForDiscovery | e22bc3ef-20a4-4173-a3c1-66d4f295e954 |