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Evidence for biological markers of tinnitus: a systematic review

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dc.contributor.authorHaider, Haúla F.
dc.contributor.authorHoare, Derek J.
dc.contributor.authorRibeiro, Sara F.
dc.contributor.authorRibeiro, Diogo
dc.contributor.authorCaria, Helena
dc.contributor.authorTrigueiros, Nuno
dc.contributor.authorBorrego, Luís
dc.contributor.authorSzczepek, Agnieszka J.
dc.contributor.authorPapoila, Ana L.
dc.contributor.authorElarbed, Asma
dc.contributor.authorMartins, Maria da Luz
dc.contributor.authorPaço, João
dc.contributor.authorSereda, Magdalena
dc.date.accessioned2024-02-15T11:01:59Z
dc.date.available2024-02-15T11:01:59Z
dc.date.issued2021
dc.description.abstractSubjective tinnitus is a phantom sound heard only by the affected person and may be a symptom of various diseases. Tinnitus diagnosis and monitoring is based on subjective audiometric and psychometric methods. This review aimed to synthesize evidence for tinnitus presence or its severity. We searched several electronic databases, citation searches of the included primary studies through Web of Science, and further hand searches. At least two authors performed all systematic review steps. Sixty-two records were included and were categorized according the biological variable. Evidence for possible tinnitus biomarkers come from oxidative stress, interleukins, steroids and neurotransmitters categories. We found conflicting evidence for full blood count, vitamins, lipid profile, neurotrophic factors, or inorganic ions. There was no evidence for an association between tinnitus and the remaining categories. The current review evidences that larger studies, with stricter exclusion criteria and powerful harmonized methodological design are needed.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationHaider, H. F., Hoare, D. J., Ribeiro, S. F., Ribeiro, D., Caria, H., Trigueiros, N., Borrego, L. M., Szczepek, A. J., Papoila, A. L., Elarbed, A., Martins, M. L., Paço, J., & Sereda, M. (2021). Evidence for biological markers of tinnitus: A systematic review, In B. Langguth, T. Kleinjung, D. De Ridder, W. Schlee, S. Vanneste (eds), Progress in Brain Research, Elsevier, 262pt_PT
dc.identifier.doihttps://doi.org/10.1016/bs.pbr.2021.01.022pt_PT
dc.identifier.isbn978-0128223758
dc.identifier.urihttp://hdl.handle.net/10400.26/49848
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.titleEvidence for biological markers of tinnitus: a systematic reviewpt_PT
dc.typebook part
dspace.entity.typePublication
rcaap.rightsclosedAccesspt_PT
rcaap.typebookPartpt_PT

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