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Autopsy in adults with congenital heart disease (ACHD)

2020Journal article Open access
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dc.contributor.authorAngelini, Annalisa
dc.contributor.authordi Gioia, Cira
dc.contributor.authorDoran, Helen
dc.contributor.authorFedrigo, Marny
dc.contributor.authorHenriques de Gouveia, Rosa
dc.contributor.authorHo, Siew Yen
dc.contributor.authorLeone, Ornella
dc.contributor.authorSheppard, Mary N
dc.contributor.authorThiene, Gaetano
dc.contributor.authorDimopoulos, Konstantinos
dc.contributor.authorMulder, Barbara
dc.contributor.authorPadalino, Massimo
dc.contributor.authorvan der Wal, Allard C
dc.date.accessioned2022-10-14T11:27:22Z
dc.date.available2022-10-14T11:27:22Z
dc.date.issued2020
dc.description.abstractThe adult congenital heart diseases (ACHD) population is exceeding the pediatric congenital heart diseases (CHD) population and is progressively expanding each year, representing more than 90% of patients with CHD. Of these, about 75% have undergone surgical and/or percutaneous intervention for palliation or correction. Autopsy can be a very challenging procedure in ACHD patients. The approach and protocol to be used may vary depending on whether the pathologists are facing native disease without surgical or percutaneous interventions, but with various degrees of cardiac remodeling, or previously palliated or corrected CHD. Moreover, interventions for the same condition have evolved over the last decades, as has perioperative myocardial preservations and postoperative care, with different long-term sequelae depending on the era in which patients were operated on. Careful clinicopathological correlation is, thus, required to assist the pathologist in performing the autopsy and reaching a diagnosis regarding the cause of death. Due to the heterogeneity of the structural abnormalities, and the wide variety of surgical and interventional procedures, there are no standard methods for dissecting the heart at autopsy. In this paper, we describe the most common types of CHDs that a pathologist could encounter at autopsy, including the various types of surgical and percutaneous procedures and major pathological manifestations. We also propose a practical systematic approach to the autopsy of ACHD patients.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationAngelini, A., di Gioia, C., Doran, H., Fedrigo, M., Henriques de Gouveia, R., Ho, S. Y., Leone, O., Sheppard, M. N., Thiene, G., Dimopoulos, K., Mulder, B., Padalino, M., van der Wal, A. C., & Association for European Cardiovascular Pathology (AECVP) (2020). Autopsy in adults with congenital heart disease (ACHD). Virchows Archiv : an international journal of pathology, 476(6), 797–820pt_PT
dc.identifier.doi10.1007/s00428-020-02779-8pt_PT
dc.identifier.issn1432-2307
dc.identifier.urihttp://hdl.handle.net/10400.26/41925
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringer Verlagpt_PT
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s00428-020-02779-8pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAutopsypt_PT
dc.subjectCardiovascular pathologypt_PT
dc.subjectCongenital heart diseasespt_PT
dc.subjectAdult congenital heart diseasespt_PT
dc.subjectProtocolpt_PT
dc.titleAutopsy in adults with congenital heart disease (ACHD)pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceBerlin, New Yorkpt_PT
oaire.citation.endPage820pt_PT
oaire.citation.issue6pt_PT
oaire.citation.startPage797pt_PT
oaire.citation.titleVirchows Archiv: an international journal of pathologypt_PT
oaire.citation.volume476pt_PT
person.familyNameHenriques de Gouveia
person.givenNameRosa
person.identifier.ciencia-id4216-8817-F6C8
person.identifier.orcid0000-0002-6728-7603
person.identifier.scopus-author-id6506051985
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicatione81b61c9-c515-41d4-b375-80554884b1ca
relation.isAuthorOfPublication.latestForDiscoverye81b61c9-c515-41d4-b375-80554884b1ca

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