Publication
Incident risk factors as predictors of HIV seroconversion in the Lisbon cohort of men who have sex with men: first results, 2011–2014
dc.contributor.author | Meireles, P | |
dc.contributor.author | Lucas, R | |
dc.contributor.author | Carvalho, C | |
dc.contributor.author | Fuertes, Ricardo | |
dc.contributor.author | Brito, J | |
dc.contributor.author | Campos, M J | |
dc.contributor.author | Mendão, Luís | |
dc.contributor.author | Barros, H | |
dc.date.accessioned | 2024-09-19T09:43:35Z | |
dc.date.available | 2024-09-19T09:43:35Z | |
dc.date.issued | 2015 | |
dc.description.abstract | HIV incidence in men who have sex with men (MSM) is increasing in western countries, including Portugal. We aimed to estimate HIV incidence and to assess how individual short-term changes in exposures over time predict seroconversion. We evaluated participants of an open cohort of HIV-negative MSM enrolled after testing at a community-based voluntary HIV counselling and testing centre in Lisbon. At each evaluation a structured questionnaire was completed and HIV status was ascertained using rapid followed by confirmatory testing. Between April 2011 and February 2014, 804 MSM were followed for a total of 893 person-years. Predictors of HIV seroconversion were identified using Poisson generalised linear regression. The overall seroincidence was 2.80/100 person-years (95% confidence interval: 1.89–4.14). Men who seroconverted had a higher mean number of tests per year. Seroconversions were significantly associated with partner disclosure of HIV status during follow-up, newly-adopted unprotected anal intercourse (UAI) with a steady partner and being newly-diagnosed with syphilis during follow-up. Likewise, sexual intercourse with HIV-positive men, having an HIV-positive steady partner at least once during follow-up and persistent UAI with occasional partners were predictors of seroconversion. High HIV incidence in this cohort is likely driven by short-term contextual and behavioural changes during follow-up. | pt_PT |
dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
dc.identifier.doi | 10.2807/1560-7917.ES2015.20.14.21091 | pt_PT |
dc.identifier.uri | http://hdl.handle.net/10400.26/52111 | |
dc.language.iso | eng | pt_PT |
dc.peerreviewed | yes | pt_PT |
dc.subject | HIV incidence | pt_PT |
dc.subject | Men who have sex with men | pt_PT |
dc.subject | Cohort | pt_PT |
dc.title | Incident risk factors as predictors of HIV seroconversion in the Lisbon cohort of men who have sex with men: first results, 2011–2014 | pt_PT |
dc.type | journal article | |
dspace.entity.type | Publication | |
oaire.citation.issue | 14 | pt_PT |
oaire.citation.title | Eurosurveillance | pt_PT |
oaire.citation.volume | 20 | pt_PT |
person.familyName | Fuertes | |
person.familyName | Penim Mendão | |
person.givenName | Ricardo | |
person.givenName | Luís Manuel | |
person.identifier | AAW-2241-2021 | |
person.identifier.ciencia-id | A615-08E1-6C13 | |
person.identifier.ciencia-id | AA16-B94D-A1A0 | |
person.identifier.orcid | 0000-0002-8562-2014 | |
person.identifier.orcid | 0000-0001-7595-4499 | |
rcaap.rights | openAccess | pt_PT |
rcaap.type | article | pt_PT |
relation.isAuthorOfPublication | 16c8ffa4-73eb-479b-a64f-ba317a6dcd89 | |
relation.isAuthorOfPublication | 29ca9078-add3-4e8b-a989-42af18fac73b | |
relation.isAuthorOfPublication.latestForDiscovery | 29ca9078-add3-4e8b-a989-42af18fac73b |
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