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Incident risk factors as predictors of HIV seroconversion in the Lisbon cohort of men who have sex with men: first results, 2011–2014

dc.contributor.authorMeireles, P
dc.contributor.authorLucas, R
dc.contributor.authorCarvalho, C
dc.contributor.authorFuertes, Ricardo
dc.contributor.authorBrito, J
dc.contributor.authorCampos, M J
dc.contributor.authorMendão, Luís
dc.contributor.authorBarros, H
dc.date.accessioned2024-09-19T09:43:35Z
dc.date.available2024-09-19T09:43:35Z
dc.date.issued2015
dc.description.abstractHIV incidence in men who have sex with men (MSM) is increasing in western countries, including Portugal. We aimed to estimate HIV incidence and to assess how individual short-term changes in exposures over time predict seroconversion. We evaluated participants of an open cohort of HIV-negative MSM enrolled after testing at a community-based voluntary HIV counselling and testing centre in Lisbon. At each evaluation a structured questionnaire was completed and HIV status was ascertained using rapid followed by confirmatory testing. Between April 2011 and February 2014, 804 MSM were followed for a total of 893 person-years. Predictors of HIV seroconversion were identified using Poisson generalised linear regression. The overall seroincidence was 2.80/100 person-years (95% confidence interval: 1.89–4.14). Men who seroconverted had a higher mean number of tests per year. Seroconversions were significantly associated with partner disclosure of HIV status during follow-up, newly-adopted unprotected anal intercourse (UAI) with a steady partner and being newly-diagnosed with syphilis during follow-up. Likewise, sexual intercourse with HIV-positive men, having an HIV-positive steady partner at least once during follow-up and persistent UAI with occasional partners were predictors of seroconversion. High HIV incidence in this cohort is likely driven by short-term contextual and behavioural changes during follow-up.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.2807/1560-7917.ES2015.20.14.21091pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/52111
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectHIV incidencept_PT
dc.subjectMen who have sex with menpt_PT
dc.subjectCohortpt_PT
dc.titleIncident risk factors as predictors of HIV seroconversion in the Lisbon cohort of men who have sex with men: first results, 2011–2014pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue14pt_PT
oaire.citation.titleEurosurveillancept_PT
oaire.citation.volume20pt_PT
person.familyNameFuertes
person.familyNamePenim Mendão
person.givenNameRicardo
person.givenNameLuís Manuel
person.identifierAAW-2241-2021
person.identifier.ciencia-idA615-08E1-6C13
person.identifier.ciencia-idAA16-B94D-A1A0
person.identifier.orcid0000-0002-8562-2014
person.identifier.orcid0000-0001-7595-4499
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication16c8ffa4-73eb-479b-a64f-ba317a6dcd89
relation.isAuthorOfPublication29ca9078-add3-4e8b-a989-42af18fac73b
relation.isAuthorOfPublication.latestForDiscovery29ca9078-add3-4e8b-a989-42af18fac73b

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