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A rare cause of agranulocytosis
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Orientador(es)
Resumo(s)
Clozapine, an atypical antipsychotic agent, is useful in the treatment of patients with psychotic symptoms. However, severe adverse effects, such as agranulocytosis, can restrict its indications. We present a case of a 42-year-old Caucasian woman with a 4-year history of persistent delusion disorder, who presented with fatigue
and fever and was ultimately diagnosed with agranulocytosis due to clozapine. Clozapine-induced granulocytosis is an uncommon condition, but potentially fatal in consequences. Each patient with an episode of agranulocytosis should be assessed individually, with special attention to risk factors. Upon that, the decision about
clozapine rechallenge or withdrawal should be made
Descrição
Palavras-chave
agranulocytosis Clozapine Região Autónoma da Madeira Clozapine - risk factors Portugal Madeira Island
Contexto Educativo
Citação
Clin Case Rep Rev, 2021 doi: 10.15761/CCRR.1000501
Editora
OAT-Open Acess Text