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Biological treatments for temporomandibular joint disc disorders: strategies in tissue engineering

2021-06-23Journal article Open access
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dc.contributor.authorTrindade, Daniela
dc.contributor.authorCordeiro, Rachel
dc.contributor.authorCardoso, Henrique José
dc.contributor.authorDF, Angelo
dc.contributor.authorAlves, Nuno
dc.contributor.authorMoura, Carla
dc.date.accessioned2022-04-07T17:25:38Z
dc.date.available2022-04-07T17:25:38Z
dc.date.issued2021-06-23
dc.description.abstractThe temporomandibular joint (TMJ) is an important structure for the masticatory systemand the pathologies associated with it affect a large part of the population and impair people’slifestyle. It comprises an articular disc, that presents low regeneration capacities and the existingclinical options for repairing it are not effective. This way, it is imperative to achieve a permanentsolution to guarantee a good quality of life for people who suffer from these pathologies. Completeknowledge of the unique characteristics of the disc will make it easier to achieve a successful tissueengineering (TE) construct. Thus, the search for an effective, safe and lasting solution has alreadystarted, including materials that replace the disc, is currently growing. The search for a solutionbased on TE approaches, which involve regenerating the disc. The present work revises the TMJ disccharacteristics and its associated diseases. The different materials used for a total disc replacementare presented, highlighting the TE area. A special focus on future trends in the field and part of thesolution for the TMJ problems described in this review will involve the development of a promisingengineered disc approach through the use of decellularized extracellular matrices.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doihttps://doi.org/10.3390/biom11070933pt_PT
dc.identifier.issn2218-273X
dc.identifier.urihttp://hdl.handle.net/10400.26/40168
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPI Open Access Journalspt_PT
dc.relationCentre for Rapid and Sustainable Product Development
dc.subjectTemporomandibular joint discpt_PT
dc.subjectFibrocartilagept_PT
dc.subjectDisc dysfunctionspt_PT
dc.subjectTissue engineeringpt_PT
dc.subjectDecellularizationpt_PT
dc.titleBiological treatments for temporomandibular joint disc disorders: strategies in tissue engineeringpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleCentre for Rapid and Sustainable Product Development
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04044%2F2020/PT
oaire.citation.endPage17pt_PT
oaire.citation.issue7pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleBiomoleculespt_PT
oaire.citation.volume11pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameÂngelo
person.givenNameDavid
person.identifier.ciencia-id2C1B-F1D5-5A08
person.identifier.orcid0000-0001-8411-9946
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication92e38866-7ea3-47a4-8445-dce2aca3c9ca
relation.isAuthorOfPublication.latestForDiscovery92e38866-7ea3-47a4-8445-dce2aca3c9ca
relation.isProjectOfPublication9eb63bd4-f59b-48aa-957a-8181cfc82daa
relation.isProjectOfPublication.latestForDiscovery9eb63bd4-f59b-48aa-957a-8181cfc82daa

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