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Conservative Management of Asymptomatic Adnexal Masses Classified as Benign by the IOTA ADNEX Model: A Prospective Multicenter Portuguese Study

dc.contributor.authorBrito, ME
dc.contributor.authorBorges, A
dc.contributor.authorRodrigues, S
dc.contributor.authorAmbrósio, P
dc.contributor.authorCondeço, R
dc.contributor.authorLacerda, A
dc.contributor.authorBernardo, MJ
dc.contributor.authorPinto, P
dc.contributor.authorDjokovic, D
dc.date.accessioned2023-02-05T16:38:11Z
dc.date.available2023-02-05T16:38:11Z
dc.date.issued2021
dc.description.abstractThis prospective multicentric study aiming to determine the incidence of complications (malignant transformation, torsion or rupture) during conservative management of adnexal masses was performed in two Portuguese tertiary referral hospitals. It included ≥18-year-old, non-pregnant patients with asymptomatic adnexal masses (associated IOTA ADNEX risk of malignancy < 10%) sonographically diagnosed between January 2016 and December 2020. Conservative patient management consisted of serial clinical and ultrasound assessment up to 60 months of follow-up, spontaneous resolution of the formation or surgical excision (median follow-up: 17.8; range 9-48 months). From the 573 masses monitored (328 premenopausal and 245 postmenopausal adnexal masses), no complications were observed in 99.5%. The annual lesion growth rates and increases in morphological complexity were similar in the premenopausal and postmenopausal patients. Spontaneous resolution, evidenced in 16.4% of the patients, was more common in the premenopausal group (p < 0.05). Surgical intervention was performed in 18.4% of the cases; one borderline and one invasive FIGO IA stage cancer were diagnosed. There was an isolated case of ovary torsion (0.17%). These data support conservative management as a safe option for sonographically benign, stable and asymptomatic adnexal masses before and after menopause and highlight the need for expedite treatment of symptomatic or increased-morphological-complexity lesions.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationDiagnostics (Basel) . 2021 Oct 27;11(11):1992.pt_PT
dc.identifier.doi10.3390/diagnostics11111992pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/43623
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectDoenças dos Anexospt_PT
dc.subjectNeoplasias dos Ováriospt_PT
dc.subjectAdnexal Diseasespt_PT
dc.subjectOvarian Neoplasmspt_PT
dc.titleConservative Management of Asymptomatic Adnexal Masses Classified as Benign by the IOTA ADNEX Model: A Prospective Multicenter Portuguese Studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue11pt_PT
oaire.citation.startPage1992pt_PT
oaire.citation.titleDiagnosticspt_PT
oaire.citation.volume11pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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