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Critically ill patients with high predicted mortality: Incidence and outcome

datacite.subject.fosCiências Médicas
dc.contributor.authorOliveira, André; Vieira, Tatiana; Rodrigues, Ana; Jorge, Núria; Tavares, Luís; Costa, Laura; Paiva, José Artur; Gonçalves Pereira, João
dc.date.accessioned2025-06-02T14:13:06Z
dc.date.available2025-06-02T14:13:06Z
dc.date.issued2023
dc.description.abstractAbstract Objective: As calculated by the severity scores, an unknown number of patients are admitted to the Intensive Care Unit (ICU) with a very high risk of death. Clinical studies have poorly addressed this population, and their prognosis is largely unknown. Design: Post hoc analysis of a multicenter, cohort, longitudinal, observational, retrospective study (CIMbA). Setting: Sixteen Portuguese multipurpose ICUs. Patients: Patients with a Simplified Acute Physiology Score II (SAPS II) predicted hospital mor tality above 80% on admission to the ICU (high-risk group); A comparison with the remaining patients was obtained. Interventions: None. Main Variables of Interest: Hospital, 30 days, 1 year mortality. Results: We identified 4546 patients (59.9% male), 12.2% of the whole population. Their SAPS II predicted hospital mortality was 89.0 ± 5.8%, whilst the observed mortality was lower, 61.0%. This group had higher mortality, both during the first 30 days (aHR 3.52 [95% CI 3.34---3.71]) and from day 31 to day 365 after ICU admission (aHR 1.14 [95%CI 1.04---1.26]), respectively. However, their hospital standardized mortality ratio was similar to the other patients (0.69 vs. 0.69, P = .92). At one year of follow-up, 30% of patients in the high-risk group were alive. Conclusions: Roughly 12% of patients admitted to the ICU for more than 24 h had a SAPS II score predicted mortality above 80%. Their hospital standardized mortality was similar to the less severe population and 30% were alive after one year of follow-up.por
dc.identifier.doi10.1016/j.medin.2023.10.003
dc.identifier.urihttp://hdl.handle.net/10400.26/57917
dc.language.isoeng
dc.peerreviewedyes
dc.relation.hasversionhttps://doi.org/10.1016/j.medin.2023.10.003
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleCritically ill patients with high predicted mortality: Incidence and outcomepor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleMedicina Intensiva
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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